BACKGROUND

Ganglioneuroma is a benign neoplasm of the peripheral nervous system originating from the tissue of the sympathetic ganglia or the adrenal medulla. Neurogenic tumors of the mediastinum account for up to 40% of all tumors of the posterior mediastinum in children and adolescents, and are an extremely rare pathology among young and mature people (up to 6% of all neoplasms of the posterior mediastinum). In women, this pathology is more common.

CLINICAL CASE

Woman 39 years old. asked for medical help with non-specific complaints of shortness of breath. During the examination, based on the results of a CT scan, a diagnosis of a neoplasm of the posterior mediastinum of unclear etiology was established, in the differential diagnostic series — a neurogenic tumor of the posterior mediastinum. Surgical treatment was performed in the amount of right-sided videothoracoscopy, removal of the neoplasm of the posterior mediastinum. The surgical material was studied by morphological and immunohistochemical research methods. A diagnosis of Ganglioneuroma of the posterior mediastinum was established.

CONCLUSION

Ganglioneuroma of the posterior mediastinum is a rare disease. Due to the peculiarities of the topographic features of the neoplasm, morphological verification is not always possible. The decision on surgical treatment of the patient should be made for each patient individually, taking into account all available data on the patient’s health, the topography of the neoplasm and its characteristics in CT of the chest organs. The histological picture of this disease is not always obvious, it is recommended to perform an immunohistochemical study (Synaptophysin, S100) of the surgical material for final verification. The clinical prognosis is favorable with radical surgical treatment and does not require chemo- or radiation therapy.