The accumulation of experience performing laparoscopic procedures adopted to illustrate using the learning curve. The literature describes several models to represent the dynamics of the accumulation of experience in the evaluation of various minimally invasive procedures. However, there is no single objective method for the construction of a learning curve. To date, the learning curve for laparoscopic pancreatoduodenectomy (LDPR), one of the most complex operations in abdominal surgery, not widely described in the literature. Several models for the construction of a learning curve: a linear function and non-linear regression, exponential model, the spline regression and risk of failure coupled analysis of the cumulative sum amount. According to a graphical analysis of the learning curve LDPR ends in 47 operations.