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Lapshina A.M.

National Medical Research Center for Endocrinology of the Ministry of Health of Russia

Pigarova E.A.

Endocrinology Research Centre

Abrosimov A.Yu.

National Medical Research Center for Endocrinology of the Ministry of Health of Russia

Algorithm for morphological diagnosis of neoplasms in the chiasmal-sellar region

Authors:

Lapshina A.M., Pigarova E.A., Abrosimov A.Yu.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2021;83(6): 60‑70

DOI: 10.17116/patol20218306160

Read: 3636 times

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Table of contents

ALGORITHM FOR MORPHOLOGICAL DIAGNOSIS OF NEOPLASMS IN THE CHIASMAL-SELLAR REGION
ALGORITHM FOR MORPHOLOGICAL DIAGNOSIS OF NEOPLASMS IN THE CHIASMAL-SELLAR REGION

To cite this article:

Lapshina AM, Pigarova EA, Abrosimov AYu. Algorithm for morphological diagnosis of neoplasms in the chiasmal-sellar region. Russian Journal of Archive of Pathology. 2021;83(6):60‑70. (In Russ.)
https://doi.org/10.17116/patol20218306160

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

In the Turkish saddle area, there is a wide variety of pathological processes, the vast majority of which present as tumors of various origins (up to 90%). For a clear morphological verification of the diagnosis, it is proposed to use a diagnostic algorithm that includes the stages of differential diagnosis of normal adenohypophysis and neurohypophysis with tumors in the anterior and posterior lobes of the pituitary gland, non-pituitary origin neoplasms, as well as with non-tumor pathological processes (inflammation, cystic masses, and hyperplasia). For morphological diagnosis, histochemical and immunohistochemical methods are recommended using various staining techniques (silver impregnation, periodic acid Schiff reaction) of tissue specimens and antibody panels (pituitary hormones, low-molecular cytokeratins, pituitary transcription factors, neuroendocrine markers, etc.).

Keywords:

tumors in the anterior and posterior lobes of the pituitary gland
hypophysitis
Rathke cleft cyst

Authors:

Lapshina A.M.

National Medical Research Center for Endocrinology of the Ministry of Health of Russia

Pigarova E.A.

Endocrinology Research Centre

Abrosimov A.Yu.

National Medical Research Center for Endocrinology of the Ministry of Health of Russia

Received:

27.07.2021

Accepted:

17.09.2021

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References:

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