Skin morphology in congenital ichthyosis (Arlequin fetus)

Rastoltsev K.V.; Lantsov D.S.; Kishchenko N.V.; Al'banova V.I.; Belikov A.N.; Komleva L.F.

doi:https://doi.org/10.17116/patol201577239-42

Rastoltsev K.V.

Unit of Pathologic Anatomy, Kaluga Regional Children’s Hospital

Lantsov D.S.

Unit of Pathologic Anatomy, Kaluga Regional Oncology Dispensary

Kishchenko N.V.

Unit of Pathologic Anatomy, Kaluga Regional Oncology Dispensary

Al'banova V.I.

FPPOV Pervogo MGMU im. I.M. Sechenova

Belikov A.N.

Kaluga Regional Dermatovenereological Dispensary, Russian Federation

Komleva L.F.

Kaluga Regional Dermatovenereological Dispensary, Russian Federation

Skin morphology in congenital ichthyosis (Arlequin fetus)

Authors:

Rastoltsev K.V., Lantsov D.S., Kishchenko N.V., Al'banova V.I., Belikov A.N., Komleva L.F.

More about the authors

Journal: Russian Journal of Archive of Pathology. 2015;77(2): 39‑42

DOI: 10.17116/patol201577239-42

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To cite this article:

Rastoltsev KV, Lantsov DS, Kishchenko NV, Al'banova VI, Belikov AN, Komleva LF. Skin morphology in congenital ichthyosis (Arlequin fetus). Russian Journal of Archive of Pathology. 2015;77(2):39‑42. (In Russ.)
https://doi.org/10.17116/patol201577239-42

Подписка 2026 Архив патологии (Russian Journal of Archive of Pathology)

Использование инфографики авторами научных работ

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Abstract:

The paper describes a skin morphological examination using an immunohistochemical study (Ki-67, cytokeratin (CK) 5/6, and CK LMW) in a dead 4-month-old girl with congenital ichthyosis (Harlequin ichthyosis (HI)). There is impaired proliferative activity, abnormalities in epidermal differentiation with abnormal CK LMW synthesis, and those in the differentiation of the skin appendages. There are also pronounced sclerotic changes with a predominance of reticulin fibers, derma, and its vessels. The patient with HI and trichoepithelioma is noted to have the similar immunohistochemical phenotype of hair bulbs.

Keywords:

congenital ichthyosis

Harlequin ichthyosis

skin

immunohistochemical study

Authors:

Rastoltsev K.V.

Unit of Pathologic Anatomy, Kaluga Regional Children’s Hospital

Lantsov D.S.

Unit of Pathologic Anatomy, Kaluga Regional Oncology Dispensary

Kishchenko N.V.

Unit of Pathologic Anatomy, Kaluga Regional Oncology Dispensary

Al'banova V.I.

FPPOV Pervogo MGMU im. I.M. Sechenova

Belikov A.N.

Kaluga Regional Dermatovenereological Dispensary, Russian Federation

Komleva L.F.

Kaluga Regional Dermatovenereological Dispensary, Russian Federation

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References:

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