Currently, outpatient medical services require adequate anesthetic support with the use of the latest generation of anesthetics. Anesthetic methods should be highly qualitative, ensure rapid recovery of the central nervous system and minimize complications and side effects. The features of anesthesia in outpatient conditions and perioperative safety in patients with cerebral palsy are reviewed in the article. Cerebral palsy is a complex of symptoms caused by various lesions of the central nervous system. Neurological dysfunction can vary from mild paresis with normal cognitive status to severe spasticity with mental retardation. An optimal technique of general anesthesia for outpatient application is formulated for patients with cerebral palsy. Perioperative safety in these patients is only ensured by adequate antinociceptive protection and controlled hemodynamics. Routine local anesthesia in outpatient practice is not rational due to frequent allergic reactions and high toxicity of local anesthetic drugs. General anesthesia in outpatient surgery reduces the risk of nosocomial infection, psycho-emotional stress of patients and is valuable to expand surgical intervention with the same surgical quality.