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Abdullaev A.N.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Dzhindzhikhadze R.S.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia;
Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Polyakov A.V.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Gadzhiagaev V.S.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Zaitsev A.D.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Salyamova E.I.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Approaches in microsurgery for olfactory meningiomas: a systematic review and meta-analysis

Authors:

Abdullaev A.N., Dzhindzhikhadze R.S., Polyakov A.V., Gadzhiagaev V.S., Zaitsev A.D., Salyamova E.I.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2026;90(2): 103‑111

DOI: 10.17116/neiro202690021103

Read: 602 times

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Table of contents

APPROACHES IN MICROSURGERY FOR OLFACTORY MENINGIOMAS: A SYSTEMATIC REVIEW AND META-ANALYSIS
APPROACHES IN MICROSURGERY FOR OLFACTORY MENINGIOMAS: A SYSTEMATIC REVIEW AND META-ANALYSIS

To cite this article:

Abdullaev AN, Dzhindzhikhadze RS, Polyakov AV, Gadzhiagaev VS, Zaitsev AD, Salyamova EI. Approaches in microsurgery for olfactory meningiomas: a systematic review and meta-analysis. Burdenko's Journal of Neurosurgery. 2026;90(2):103‑111. (In Russ., In Engl.)
https://doi.org/10.17116/neiro202690021103

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Olfactory meningiomas are common neoplasms accounting for 4.5—18% of all intracranial meningiomas. Currently, transcranial (pterional, unilateral subfrontal, bilateral subfrontal, interhemispheric and through the frontal sinus) and endoscopic endonasal approaches are actively used.

OBJECTIVE

To study the efficacy and safety of various surgical approaches to olfactory meningiomas.

MATERIAL AND METHODS

The study included reports with data on clinical manifestations, surgical approach, extent of resection and postoperative complications in patients with olfactory meningiomas. Among 7.588 manuscripts, we enrolled 6.912 articles into screening after duplicate removal. There were 471 articles after title evaluation and 30 manuscripts after abstract review. After full-text review, 15 most relevant articles were selected for final analysis.

RESULTS

Meta-analysis included 634 patients with olfactory meningiomas. The most common preoperative symptom was olfactory impairment (hyposmia/anosmia) (390 (62%) patients). The least common symptom was visual impairment (260 (41%) patients). Psychoemotional and/or cognitive impairment was observed in 270 (43%) patients. Bilateral subfrontal approach was the most common (226 (36%) cases), while interhemispheric access was the rarest (25 (4%) cases). Pterional approach was used in 100 (16%) cases, supraorbital approach in 95 (15%), endoscopic transnasal approach in 138 (22%) cases, and resection through the frontal sinus in 50 (8%) cases. Tumor resection Simpson I / II was achieved in 513 (81%) cases.

CONCLUSION

Surgery is the primary treatment for olfactory meningiomas. Optimal surgical approach should be determined after a comprehensive assessment of several factors, including tumor size and growth direction, clinical manifestations, severity of perifocal edema and individual anatomical features (particularly, dimensions of paranasal sinuses).

Keywords:

olfactory meningioma
approaches to anterior cranial fossa base
transnasal approaches to anterior cranial fossa

Authors:

Abdullaev A.N.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Dzhindzhikhadze R.S.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia;
Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Polyakov A.V.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Gadzhiagaev V.S.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Zaitsev A.D.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Salyamova E.I.

Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

Received:

14.08.2025

Accepted:

26.11.2025

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