Combined use of biomaterials and revascularisation in autoplasty of ulnar nerve

Fedyakov AG, Dreval ON, Gorozhanin AV, et al. . Combined use of biomaterials and revascularisation in autoplasty of ulnar nerve. Burdenko's Journal of Neurosurgery. 2024;88(5):87‑92. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20248805187

Подписка 2025-2 (Burdenko's Journal of Neurosurgery)

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Surgical treatment of peripheral nerve injuries is effective in only 50% of cases. This is primarily due to the significant extent of the diastasis between the fragments of the damaged nerve, in which autoplasty has to be performed. The drawbacks of this technique are the formation of scar tissue, possible necrotisation of the autograft, mismatch of the donor and recipient nerve diameters. In order to overcome these drawbacks and improve the efficiency of surgical intervention, the study presents a clinical case of successful multifascicular ulnar nerve autoplasty with the use of domestic biodegradable biomaterials SpheroGel and ElastoPob, revascularization of the autograft with a connective tissue flap on a vascular pedicle. A persistent regression of local pain syndrome was observed in the early postoperative period. The effectiveness of the performed surgical intervention was confirmed by ultrasound examination: there was no evidence of neuroma in the area of the operation, regeneration of nerve bundles was noted at the site of stitching. Positive dynamics was observed in the results of VAS, DN4, DASH questionnaires.

Keywords:

peripheral nerve damage

autoplasty

biomaterials

nerve regeneration

graft revascularization

Authors:

Fedyakov A.G.

Botkin City Clinical Hospital;
Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0002-8807-3874

Dreval O.N.

Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0002-8944-9837

Gorozhanin A.V.

Botkin City Clinical Hospital;
Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0002-3593-7034

Grekov D.N.

Botkin City Clinical Hospital

ORCID: 0000-0001-8391-1210

Sidneva L.A.

Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0002-9809-525X

Plieva Z.Kh.

Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0003-1297-1616

Razin M.A.

Botkin City Clinical Hospital;
Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0002-4408-8943

Chapandze G.N.

Russian Medical Academy for Continuous Professional Education

ORCID: 0000-0002-5994-6349

Received:

06.05.2024

Accepted:

21.06.2024

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