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Konovalov A.N.

Burdenko Neurosurgical Center

Chernov I.V.

Burdenko Neurosurgical Center

Ryzhova M.V.

Burdenko Neurosurgical Center

Pitskhelauri D.I.

Burdenko Neurosurgical Center

Kushel Yu.V.

Priorov National Medical Research Center of Traumatology and Orthopedics

Astafieva L.I.

Burdenko Neurosurgical Center

Sharipov O.I.

N.N. Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation

Klochkova I.S.

Burdenko Neurosurgical Center

Sidneva Yu.G.

Research Institute of Emergency Pediatric Surgery and Traumatology

Snigireva G.P.

Burdenko Neurosurgical Center

Kalinin P.L.

Burdenko Neurosurgical Center

Chordoid gliomas of the third ventricle

Authors:

Konovalov A.N., Chernov I.V., Ryzhova M.V., Pitskhelauri D.I., Kushel Yu.V., Astafieva L.I., Sharipov O.I., Klochkova I.S., Sidneva Yu.G., Snigireva G.P., Kalinin P.L.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2023;87(6): 14‑24

DOI: 10.17116/neiro20238706114

Read: 3265 times

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Table of contents

CHORDOID GLIOMAS OF THE THIRD VENTRICLE
CHORDOID GLIOMAS OF THE THIRD VENTRICLE

To cite this article:

Konovalov AN, Chernov IV, Ryzhova MV, et al. Chordoid gliomas of the third ventricle. Burdenko's Journal of Neurosurgery. 2023;87(6):14‑24. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20238706114

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

BACKGROUND

Chordoid glioma is a rare slow-growing tumor of the central nervous system. Available world experience includes no more than 200 cases (lesion of the third ventricle in absolute majority of cases). Recognition and treatment of chordoid glioma are currently difficult problems due to small incidence of this disease.

OBJECTIVE

To describe clinical manifestations and surgical treatment of chordoid glioma of the third ventricle considering literature data and own experience.

MATERIAL AND METHODS

There were 12 patients (6 men and 6 women) with chordoid glioma between 2004 and 2023 (10 patients with lesion of the third ventricle, 1 — lateral ventricle, 1 — pineal region). Only patients with tumors of the third ventricle were analyzed.

RESULTS

Total and subtotal resection was performed in 1 and 3 cases, respectively. Five patients underwent partial resection, 1 patient underwent biopsy. The follow-up data were available in 7 out of 10 patients (mean 25 months). Radiotherapy was performed in 4 patients (continued tumor growth in 2 cases). One patient died.

CONCLUSION

Chordoid glioma is a benign tumor predominantly localized in the third ventricle. Preoperative MRI and CT in some cases make it possible to suspect chordoid glioma and differentiate this tumor from craniopharyngioma, meningioma and pituitary adenoma by such signs as isointense signal in T1WI, hyper- or isointense signal in T2WI, homogeneous contrast enhancement and edema of basal ganglia in T2 FLAIR images. The only effective treatment for chordoid glioma is surgery. Total resection is often impossible or extremely dangerous due to location of tumor, large size and invasion of the third ventricle. Postoperative mental disorders and diabetes insipidus, including severe hypernatremia, are common that requires mandatory monitoring of water and electrolyte balance.

Keywords:

chordoid glioma

Authors:

Konovalov A.N.

Burdenko Neurosurgical Center

Chernov I.V.

Burdenko Neurosurgical Center

Ryzhova M.V.

Burdenko Neurosurgical Center

Pitskhelauri D.I.

Burdenko Neurosurgical Center

Kushel Yu.V.

Priorov National Medical Research Center of Traumatology and Orthopedics

Astafieva L.I.

Burdenko Neurosurgical Center

Sharipov O.I.

N.N. Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation

Klochkova I.S.

Burdenko Neurosurgical Center

Sidneva Yu.G.

Research Institute of Emergency Pediatric Surgery and Traumatology

Snigireva G.P.

Burdenko Neurosurgical Center

Kalinin P.L.

Burdenko Neurosurgical Center

Received:

20.03.2023

Accepted:

14.09.2023

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