Endoscopic transnasal resection of clival meningiomas

Shkarubo AN, Chernov IV, Veselkov AA, Andreev DN, Sinelnikov ME, Karnaukhov VV, Yakupova ZF. Endoscopic transnasal resection of clival meningiomas. Burdenko's Journal of Neurosurgery. 2023;87(4):27‑34. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20238704127

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

Использование инфографики авторами научных работ

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OBJECTIVE

To assess postoperative outcomes in patients with clival meningiomas.

MATERIAL AND METHODS

We analyzed 18 patients with large or giant clival meningiomas.

RESULTS

We assessed extent of resection using the scale by G. Frank and E. Pasquini (2002): total resection — 95—100%, subtotal — 80—95%, partial — 50—80%, extended biopsy — <50% of tumor. Total resection was achieved in 1 patient (5.5%), subtotal — 5 (27.8%), partial — 12 (66.7%). At the same time, brainstem decompression and regression of hydrocephalus were observed in all cases. Fourteen patients were followed-up. Median follow-up was 8.5 months. Seventeen patients underwent radiotherapy due to predominant partial and subtotal resection. Total focal dose ranged from 50 to 57 Gy in standard fractionation mode. None patient had residual tumor enlargement throughout the follow-up period. There were no lethal outcomes.

CONCLUSION

Endoscopic transnasal access to clival meningiomas in appropriate anatomical features of tumor and surrounding structures is a full-fledged alternative to transcranial treatment in these patients. This approach provides total resection and brainstem decompression. These facts increase life expectancy without deterioration of the quality of life.

Keywords:

clival meningioma

endoscopic transnasal approach

Authors:

Shkarubo A.N.

Burdenko Neurosurgical Center

ORCID: 0000-0003-3445-3115

Chernov I.V.

Burdenko Neurosurgical Center

ORCID: 0000-0002-9789-3452

Veselkov A.A.

Burdenko Neurosurgical Center

ORCID: 0000-0003-2500-3403

Andreev D.N.

Burdenko Neurosurgical Center

ORCID: 0000-0001-5473-4905

Sinelnikov M.E.

Sechenov First Moscow State Medical University (Sechenov University)

ORCID: 0000-0002-0862-6011

Karnaukhov V.V.

Burdenko Neurosurgical Center

ORCID: 0000-0002-2581-8648

Yakupova Z.F.

Peoples’ Friendship University of Russia

ORCID: 0009-0001-8525-4223

Received:

21.10.2022

Accepted:

19.05.2023

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References:

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