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Kopachev D.N.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

Bychenko V.G.

Kulakov Scientific Center for Obstetrics, Gynecology, and Perinatology, Moscow, Russia

Shkatova A.M.

Burdenko Neurosurgical Institute, Moscow, Russia

Golovteev A.L.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko"

Troitskiĭ A.A.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ, Moskva

Grinenko O.A.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko"

Hippocampal sclerosis: pathogenesis, clinical features, diagnosis, and treatment

Authors:

Kopachev D.N., Shishkina L.V., Bychenko V.G., Shkatova A.M., Golovteev A.L., Troitskiĭ A.A., Grinenko O.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2016;80(4): 109‑116

DOI: 10.17116/neiro2016804109-116

Read: 47629 times

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Table of contents

HIPPOCAMPAL SCLEROSIS: PATHOGENESIS, CLINICAL FEATURES, DIAGNOSIS, AND TREATMENT
HIPPOCAMPAL SCLEROSIS: PATHOGENESIS, CLINICAL FEATURES, DIAGNOSIS, AND TREATMENT

To cite this article:

Kopachev DN, Shishkina LV, Bychenko VG, Shkatova AM, Golovteev AL, Troitskiĭ AA, Grinenko OA. Hippocampal sclerosis: pathogenesis, clinical features, diagnosis, and treatment. Burdenko's Journal of Neurosurgery. 2016;80(4):109‑116. (In Russ., In Engl.)
https://doi.org/10.17116/neiro2016804109-116

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Hippocampal sclerosis, also known as Ammon horn sclerosis or mesial temporal sclerosis, is usually associated with intractable epilepsy and characterized by specific patterns of neuronal loss and gliosis in the medial temporal lobe structures. Hippocampal sclerosis manifests clinically as epilepsy, often intractable epilepsy; in most cases, this condition is surgically treatable. As the most common histological diagnosis in adult patients subjected to epilepsy surgery, hippocampal sclerosis is characterized by complex pathogenesis and requires a multidisciplinary approach to its diagnosis and treatment. This article reviews the pathologic features, natural history, pathogenesis, and electroclinical and MRI signs of hippocampal sclerosis.

Keywords:

hippocampus sclerosis
epilepsy surgery
symptomatic temporal lobe epilepsy

Authors:

Kopachev D.N.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

Bychenko V.G.

Kulakov Scientific Center for Obstetrics, Gynecology, and Perinatology, Moscow, Russia

Shkatova A.M.

Burdenko Neurosurgical Institute, Moscow, Russia

Golovteev A.L.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko"

Troitskiĭ A.A.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ, Moskva

Grinenko O.A.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko"

Close metadata

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