Glioneuronal tumor with neuropil-like islands in a neonate

Gorelyshev S.K.; Matuev K.B.; Shishkina L.V.; Lubnin A.Yu.; Ryzhova M.V.; Yakovlev S.B.; Kholodov B.V.; Tarasova E.M.

doi:https://doi.org/

Gorelyshev S.K.

GBU NII neĭrokhirurgii im. N.N. Burdenko

Matuev K.B.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

ORCID: 0000-0001-7045-7223

Lubnin A.Yu.

Moscow Regional Research Institute of Obstetrics and Gynecology, Ministry of Health of the Moscow Region, Moscow, Russia, N.N. Burdenko Research Institute of Neurosurgery, Moscow, Russia, Department of Obstetrics and Gynecology, M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russia

RSCI AuthorID: 370609
Scopus AuthorID: 57192157123
ORCID: 0000-0003-2595-5877

Ryzhova M.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

ORCID: 0000-0001-7206-6365

Yakovlev S.B.

Burdenko’ National medical research center of neurosurgery, Moscow, Russia

ORCID: 0000-0002-0798-2604

Kholodov B.V.

GBU NII neĭrokhirurgii im. N.N. Burdenko

Tarasova E.M.

FGBU "Nauchno-issledovatel'skiĭ institut neĭrokhirurgii im. akad. N.N. Burdenko" RAMN

Glioneuronal tumor with neuropil-like islands in a neonate

Authors:

Gorelyshev S.K., Matuev K.B., Shishkina L.V., Lubnin A.Yu., Ryzhova M.V., Yakovlev S.B., Kholodov B.V., Tarasova E.M.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2013;77(2): 50‑56

Read: 2916 times

To cite this article:

Gorelyshev SK, Matuev KB, Shishkina LV, et al. Glioneuronal tumor with neuropil-like islands in a neonate. Burdenko's Journal of Neurosurgery. 2013;77(2):50‑56. (In Russ., In Engl.)

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

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Abstract:

Glioneuronal tumor with neuropil-like islands - GTNI is a rare histopatological subtype of anaplastic astrocytoma. English-language literature contains only 43 observations, among them only 4 observations in children up to 18 years. Neuropil is an eosinophilic stained a cellular foci of tumor tissue. These cells demonstrate less proliferation activity than prevailing glial component, which is characterized by a high degree of atypia - Gr III according to WHO classification. Single reports about verification of the glioneuronal tumor with neuropil-like islands in children are supplemented with an observation of the case with tumor, located in lateral ventricular in infant with the onset of hypertension symptoms at the age of 11 months. The potential for complete removal of these tumors despite its large size and young age of the child is presented. However, the prognosis in infants with GTNI despite completeness of removal and chemotherapy might be extremely unfavorable - in case of intraventricular localization progression in the form of tumor implantation on ventricular ependyma is possible.

Keywords:

brain tumor

neonate

glioneuronal tumor with neuropil-like islands (GTNI)

Authors:

Gorelyshev S.K.

GBU NII neĭrokhirurgii im. N.N. Burdenko

Matuev K.B.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

ORCID: 0000-0001-7045-7223

Lubnin A.Yu.

RSCI AuthorID: 370609
Scopus AuthorID: 57192157123
ORCID: 0000-0003-2595-5877

Ryzhova M.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

ORCID: 0000-0001-7206-6365

Yakovlev S.B.

Burdenko’ National medical research center of neurosurgery, Moscow, Russia

ORCID: 0000-0002-0798-2604

Kholodov B.V.

GBU NII neĭrokhirurgii im. N.N. Burdenko

Tarasova E.M.

FGBU "Nauchno-issledovatel'skiĭ institut neĭrokhirurgii im. akad. N.N. Burdenko" RAMN

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