CyberKnife stereotactic radiotherapy for mass lesions of spinal cord and spine

Golanov A.V.; Gorlachev G.E.; Antipina N.A.; Konovalov N.A.; Shevelev I.H.; Vetlova E.R.; Zolotova S.V.; Galkin M.V.; Arutiunov N.V.; Tissen T.P.; Rodionov P.V.

doi:https://doi.org/

Golanov A.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Gorlachev G.E.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Antipina N.A.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Konovalov N.A.

OOO Klinika spinal'noĭ neĭrokhirurgii «Aksis»;
NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

ORCID: 0000-0003-0824-1848

Shevelev I.H.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Vetlova E.R.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Zolotova S.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Galkin M.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Arutiunov N.V.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Tissen T.P.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Rodionov P.V.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

CyberKnife stereotactic radiotherapy for mass lesions of spinal cord and spine

Authors:

Golanov A.V., Gorlachev G.E., Antipina N.A., Konovalov N.A., Shevelev I.H., Vetlova E.R., Zolotova S.V., Galkin M.V., Arutiunov N.V., Tissen T.P., Rodionov P.V.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2012;76(1): 54‑63

Read: 4997 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Golanov AV, Gorlachev GE, Antipina NA, et al. . CyberKnife stereotactic radiotherapy for mass lesions of spinal cord and spine. Burdenko's Journal of Neurosurgery. 2012;76(1):54‑63. (In Russ.)

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)

Использование инфографики авторами научных работ

Close metadata

Abstract:

Introduction of a novel technology of stereotactic radiation treatment using linear accelerators, refining of systems for visualization and guidance provided rapid development of extracranial radiosurgery. Nowadays there is a possibility of precise stereotactic irradiation of lesions with different size and localization. One of the most actual and promising indications for radiosurgery are different primary and metastatic lesions and arteriovenous malformations of spinal cord and spine. Radiosurgery and hypofractionated radiotherapy with precise dose delivery during one or several sessions allow effective and safe treatment of neoplasms with any degree of radioresistance. This paper contains analysis of the first Russian experience of stereotactic radiation treatment of lesions of spinal cord and spine using robotized system CyberKnife (Accuray Inc., USA).

Keywords:

CyberKnife

spinal cord tumor

spinal tumor

radiosurgery

hypofractionation

Authors:

Golanov A.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Gorlachev G.E.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Antipina N.A.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Konovalov N.A.

OOO Klinika spinal'noĭ neĭrokhirurgii «Aksis»;
NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

ORCID: 0000-0003-0824-1848

Shevelev I.H.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Vetlova E.R.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Zolotova S.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Galkin M.V.

FGBU "NII neĭrokhirurgii im. akad. N.N. Burdenko" RAMN, Moskva

Arutiunov N.V.

NII neĭrokhirurgii im. akad. N.N. Burdenko RAMN, Moskva

Tissen T.P.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Rodionov P.V.

FGBU "NII neĭrokhirurgii im. N.N. Burdenko" RAMN, Moskva

Close metadata

References:

Benzyl D.L., Saboori M., Mogilner A.Y. et al. Safety and efficacy of stereotactic radiosurgery for tumors of the spine. J Neurosurgery 2004; 101: Suppl 3: 413-418.
Bilsky M.H., Angelov L., Rock J. et al. Spinal radiosurgery: a neurosurgical perspective. J Radiosurg SBRT 2011; 1: 47-54.
Chang E.L., Shiu A.S., Mendel E. et al. Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. J Neurosurg Spine 2007; 7: 2: 151-160.
Gerszeten P., Mendel E., Yamada Y. Radiotherapy and radiosurgery for metastatic spine disease: what are the options, indications, and outcomes? Spine (Philadelphia Pa 1976) 2009; 34: 22: Suppl: S78-S92.
Gerszeten P.C., Burton S.A., Ozhasoglu C. et al. Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Spine 2007; 32: 2: 193-199.
Gerszeten P.C., Burton S.A., Ozhasoglu C., McCue K.J., Quinn A.E. Radiosurgery for benign intradural spinal tumors. Neurosurgery 2008; 62: 4: 887-895.
Gerszeten P.C., Germanwala A., Burton S.A. et al. Combination kyphoplasty and spinal radiosurgery: a new treatment paradigm for pathological fractures. Neurosurg Focus 2005; 18: 3: e8.
Gibbs I.C., Patil C., Gerszeten P.C., Adler J.R., Burton S. Delayed radiation-induced myelopathy after spinal radiosurgery. Neurosurgery 2009; 64: 2: Suppl: A54-A59.
Jin J.Y., Chen Q., Jin R. et al. Technical and clinical experience with spine radiosurgery: a new technology for management of localized spine metastases. Technol Cancer Res Treat 2007; 6: 2: 127-133.
Levine A.M., Coleman C., Horasek S. Stereotactic radiosurgery for the treatment of primary sarcomas and sarcoma metastases of the spine. Neurosurgery 2009; 64: 2: Suppl: A54-A59.
Moulding H.D., Elder J.B., Lis E. et al. Local disease control after decompressive surgery and adjuvant high-dose single-fraction radiosurgery for spine metastases. J Neurosurg 2003; 98: 1: Suppl: 21-30.
Rades D., Fehlauer F., Schulte R. et al. Prognostic Factors for Local Control and Survival After Metastatic Spinal Cord Compression. J Clin Oncol 2006; 24: 21: 3388-3393.
Rades D., Stalpers L.J., Hulshof M.C. et al. Effectiveness and toxicity of single-fraction radiotherapy with 1x8 Gy for metastatic spinal cord compression. Radiother Oncol 2005; 75: 1: 70-73.
Regine W.F., Ryu S., Chang E.L. Spine radiosurgery for spinal cord compression: the radiation oncologist's perspective. J Radiosurg SBRT 2011; 1: 55-61.
Rock J.P., Ryu S., Shukairy M.S. et al. Postoperative radiosurgery for malignant spinal tumors. Neurosurgery 2006; 58: 5: 891-898; discussion 891-898.
Rose P.S., Laufer I., Burch S. Risk of fracture after single fraction image-guided intensity-modulated radiation therapy to spinal metastases. J Clin Oncol 2009; 27: 30: 5075-5079.
Ryu S., Jin J.Y., Jin R. et al. Partial volume tolerance of the spinal cord and complications of single-dose radiosurgery. Cancer 2007; 109: 3: 628-636.
Ryu S.I., Chang S.D., Kim D.H. et al. Image-guided hypofractioned stereotactic radiosurgery to spinal lesions. Neurosurgery 2001; 49: 4: 838-846.
Sinclair J., Chang S.D., Gibbs I.C., Adler J.R.Jr. Cyber-Knife Radiosurgery for intramedullary spinal cord arteriovenous malformations. Robotic Radiosurg 2005; 1: 187-196.
Wu A.J., Bilsky M.H., Edgar M.A. et al. Near-complete pathological response of chordoma to high-dose single-fraction radiotherapy: case report. Neurosurgery 2009; 64: 2: E389-90; discussion E390.
Yamada Y., Bilsky M.H., Lovelock D.M. et al. High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions. Int J Radiat Oncol Biol Phys 2008; 71: 2: 484-490.