Stiff-person syndrome: a clinical observation

Isaeva N.V.; Prokopenko S.V.; Rodikov M.V.; Abroskina M.V.; Ondar V.S.; Subocheva S.A.; Ippolitova E.V.; Kuznetsov V.Yu.

doi:https://doi.org/10.17116/jnevro201911906196

Isaeva N.V.

Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia;
Regional Clinical Hospital, Krasnoyarsk, Russia

ORCID: 0000-0002-8323-7411

Prokopenko S.V.

Kafedra nervnykh bolezneĭ, traditsionnoĭ meditsiny Krasnoiarskogo gosudarstvennogo meditsinskogo universiteta im. prof. V.F. Voĭno-Iasenetskogo, Krasnoiarsk

Rodikov M.V.

Kafedra nervnykh bolezneĭ Krasnoiarskogo gosudarstvennogo meditsinskogo universiteta

Abroskina M.V.

Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk

Scopus AuthorID: 57193719760
ResearcherID: F-2353-2016
ORCID: 0000-0002-1454-1807

Ondar V.S.

Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk

Subocheva S.A.

Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia

Ippolitova E.V.

Regional Clinical Hospital, Krasnoyarsk, Russia

Kuznetsov V.Yu.

Regional Clinical Hospital, Krasnoyarsk, Russia

Stiff-person syndrome: a clinical observation

Authors:

Isaeva N.V., Prokopenko S.V., Rodikov M.V., Abroskina M.V., Ondar V.S., Subocheva S.A., Ippolitova E.V., Kuznetsov V.Yu.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(6): 96‑100

DOI: 10.17116/jnevro201911906196

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To cite this article:

Isaeva NV, Prokopenko SV, Rodikov MV, et al. Stiff-person syndrome: a clinical observation. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(6):96‑100. (In Russ.)
https://doi.org/10.17116/jnevro201911906196

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

Stiff-person syndrome (SPS) is a rare chronic neurological disease characterized by progressing muscle rigidity and painful muscle spasms. The signs of SPS are pain and stiffness in spinal, abdominal and cervical muscles, increased muscle tonus in extensor muscles of extremities, constant stiffness of paravertebral and abdominal muscles and muscle spasms. A clinical case of a SPS patient T., aged 23 years, is presented. The peculiarity of this case is additional left-sided peripheral upper extremity monoparesis, which is most likely associated with the development of left-sided compression-ischemic brachial plexopathy resulted from profound muscular tonic syndrome in the neck and shoulder girdles.

Keywords:

stiff-man syndrome

anti-GAD antibodies

peripheral paresis

Authors:

Isaeva N.V.

Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia;
Regional Clinical Hospital, Krasnoyarsk, Russia

ORCID: 0000-0002-8323-7411

Prokopenko S.V.

Kafedra nervnykh bolezneĭ, traditsionnoĭ meditsiny Krasnoiarskogo gosudarstvennogo meditsinskogo universiteta im. prof. V.F. Voĭno-Iasenetskogo, Krasnoiarsk

Rodikov M.V.

Kafedra nervnykh bolezneĭ Krasnoiarskogo gosudarstvennogo meditsinskogo universiteta

Abroskina M.V.

Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk

Scopus AuthorID: 57193719760
ResearcherID: F-2353-2016
ORCID: 0000-0002-1454-1807

Ondar V.S.

Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk

Subocheva S.A.

Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia

Ippolitova E.V.

Regional Clinical Hospital, Krasnoyarsk, Russia

Kuznetsov V.Yu.

Regional Clinical Hospital, Krasnoyarsk, Russia

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