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Zhivolupov S.A.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Onishchenko L.S.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Rashidov N.A.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Samartsev I.N.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Jakovlev E.V.

Medical Center «Admiralteyskie Verfi», St. Petersburg

Spinal mechanisms of neuroplasticity induced by neuromidin in treatment of traumatic neuropathies

Authors:

Zhivolupov S.A., Onishchenko L.S., Rashidov N.A., Samartsev I.N., Jakovlev E.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(2): 58‑64

DOI: 10.17116/jnevro20181182158-64

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SPINAL MECHANISMS OF NEUROPLASTICITY INDUCED BY NEUROMIDIN IN TREATMENT OF TRAUMATIC NEUROPATHIES
SPINAL MECHANISMS OF NEUROPLASTICITY INDUCED BY NEUROMIDIN IN TREATMENT OF TRAUMATIC NEUROPATHIES

To cite this article:

Zhivolupov SA, Onishchenko LS, Rashidov NA, Samartsev IN, Jakovlev EV. Spinal mechanisms of neuroplasticity induced by neuromidin in treatment of traumatic neuropathies. S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(2):58‑64. (In Russ.)
https://doi.org/10.17116/jnevro20181182158-64

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Objective. To analyze the spinal mechanisms of neuroplastic changes induced by neuromidin (ipidacrine) in a model of traumatic axonotomy of the sciatic nerve in rats. Material and methods. The histological study of the material from the anterior horn (lumbar portion of spinal cord) was performed in 6 rats using electron microscopy. Results and conclusion. The comparative analysis of neuromorphological changes in rats of control and main groups revealed the neuroprotective and modifying effects of neuromidin on the spinal neuroplasticity.

Keywords:

spinal neuroplasticity
neuromidin (ipidacrine)
traumatic axonotomy
electronic microscopy

Authors:

Zhivolupov S.A.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Onishchenko L.S.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Rashidov N.A.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Samartsev I.N.

Kafedra nervnykh bolezneĭ Voenno-meditsinskoĭ akademii im. S.M. Kirova, Sankt-Peterburg

Jakovlev E.V.

Medical Center «Admiralteyskie Verfi», St. Petersburg

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References:

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  4. Zhivolupov SA, Gnevyshev EN, Trufanov AG, Voronkov LV, Yurin AA, Rashidov NA, Samartsev IN, Poltavsky ID. MRI morphometry of neuroplastic changes in the brain after conservative treatment of traumatic brachial plexopathy. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2017;117(1, vyp. 2):14-27. (In Russ.)
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  6. Rosenkranz K, Rothwell JC. Differences between the effects of three plasticity inducing protocols on the organization of the human motor cortex. Eur J Neurosci. 2006;23(3):822-829. https://doi.org/10.1111/j.1460-9568.2006.04605.x
  7. Ara J, Bannerman P, Hahn A, Ramirez S, Pleasure D. Modulation of sciatic nerve expression of class 3 semaphorins by nerve injury. Neurochem Res. 2004;29(6):1153-1159. https://doi.org/10.1023/b:nere.0000023602.72354.82
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