The use of neuroleptics in the treatment of hyperkinetic behavioral disorders in children

Priputnevich D.N.; Kutashov V.A.; Chernykh D.A.; Siromyatnikova E.V.; Kuptcova D.O.

doi:https://doi.org/10.17116/jnevro20181182131-34

Priputnevich D.N.

Burdenko Voronezh State Medical University, Voronezh, Russia

Kutashov V.A.

Burdenko Voronezh State Medical University, Voronezh, Russia

Chernykh D.A.

Kafedra obshcheĭ khirurgii Sankt-Peterburgskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia, Mariinskaia bol'nitsa, Sankt-Peterburg

Siromyatnikova E.V.

Burdenko Voronezh State Medical University, Voronezh, Russia

Kuptcova D.O.

Burdenko Voronezh State Medical University, Voronezh, Russia

The use of neuroleptics in the treatment of hyperkinetic behavioral disorders in children

Authors:

Priputnevich D.N., Kutashov V.A., Chernykh D.A., Siromyatnikova E.V., Kuptcova D.O.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(2): 31‑34

DOI: 10.17116/jnevro20181182131-34

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Priputnevich DN, Kutashov VA, Chernykh DA, Siromyatnikova EV, Kuptcova DO. The use of neuroleptics in the treatment of hyperkinetic behavioral disorders in children. S.S. Korsakov Journal of Neurology and Psychiatry. 2018;118(2):31‑34. (In Russ.)
https://doi.org/10.17116/jnevro20181182131-34

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

Objective. To compare the efficacy of thioridazine and tiapride in treatment of hyperkinetic behavioral disorders (HBD) in children. Material and methods. The study included 60 children, детей, 42 boys and 18 girls, mean age 8.0±2.0 years. Patients were divided into two equal groups. The duration of the study was 30 days. The Achenbach System of Empirically Based Assessment (ASEBA) was used. Safety was assessed by sedation scores and serum prolactin levels. Results and conclusion. A positive effect of both drugs was shown. The levels of aggression and delinquency decreased significantly, while a decrease in attention levels was less pronounced. Both drugs were similar by efficacy, but tiapride had better safety profile.

Keywords:

hyperkinetic behavioral disorder

thioridazine

tiapride

ASEBA

Authors:

Priputnevich D.N.

Burdenko Voronezh State Medical University, Voronezh, Russia

Kutashov V.A.

Burdenko Voronezh State Medical University, Voronezh, Russia

Chernykh D.A.

Kafedra obshcheĭ khirurgii Sankt-Peterburgskoĭ meditsinskoĭ akademii poslediplomnogo obrazovaniia, Mariinskaia bol'nitsa, Sankt-Peterburg

Siromyatnikova E.V.

Burdenko Voronezh State Medical University, Voronezh, Russia

Kuptcova D.O.

Burdenko Voronezh State Medical University, Voronezh, Russia

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References:

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