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Zuev A.A.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

Kostenko G.V.

Pirogov National Medical Surgical Center, Moscow, Russia

Treatment of syringomyelia associated with Chiari 1 malformation

Authors:

Zuev A.A., Kostenko G.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(3): 102‑106

DOI: 10.17116/jnevro201711731102-106

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TREATMENT OF SYRINGOMYELIA ASSOCIATED WITH CHIARI 1 MALFORMATION
TREATMENT OF SYRINGOMYELIA ASSOCIATED WITH CHIARI 1 MALFORMATION

To cite this article:

Zuev AA, Kostenko GV. Treatment of syringomyelia associated with Chiari 1 malformation. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(3):102‑106. (In Russ.)
https://doi.org/10.17116/jnevro201711731102-106

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
МСФ на ЯМ
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Abstract:

Syringomyelia (SM) develops due to the disturbance of cerebrospinal fluid dynamics, spinal fixation or a spinal tumor. The disturbance of cerebrospinal fluid dynamics in the area of the foramen magnum leads to the progression of SM in Chiari 1 malformation (CM1). CM1 is the most prevalent pathology of craniovertebral junction associated with SM. The prevalence of CM1 varies from 3 to 8 per 100 000 population but SM is diagnosed in 65% of patients with CM1. Clinical symptoms of CM1 and SM include pain in the occipital area, gait disturbances due to sensitive ataxia, dissociated sensory disorders, dysphagia, paresis of the extremities. In most patients, symptoms of SM progressed over the years. The diagnosis is based on MRI results of the brain and spinal cord. Phase-contrast MRI is used to study the disturbance of cerebrospinal fluid dynamics in details. Progression of SM or CM1 symptoms needs surgical treatment — decompression of the posterior cranial fossa for the recovery of normal cerebrospinal fluid dynamics.

Keywords:

syringomyelia
Chiari 1 malformation
cerebrospinal fluid dynamics

Authors:

Zuev A.A.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

Kostenko G.V.

Pirogov National Medical Surgical Center, Moscow, Russia

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References:

  1. Klekamp J, Samii M. Syringomyelia:Diagnosis and Treatment. Berlin: Springer; 2002. doi: 10.1007/978-3-642-56023-1
  2. Gardner W. Hydrodynamic mechanism of syringomyelia: its relationship to myelocele. Journal of Neurology, Neurosurgery & Psychiatry. 1965;28(3):247-259. doi: 10.1136/jnnp.28.3.247
  3. Williams B. Investigations on the Pathogenesis of Syringomyelia. Advances in Neurosurgery. 1980;8:277-283. doi: 10.1007/978-3-642-67605-5_46.
  4. Blegvad C, Grotenhuis J, Juhler M. Syringomyelia: a practical, clinical concept for classification. Acta Neurochir. 2014;156(11):2127-2138. doi: 10.1007/s00701-014-2229-z
  5. Harbitz F, Lossius I. Extramedullary tumour. Arachnitis fibrosa cystica et ossificans. Gliosis of the medulla. Acta Psychiatrica Scandinavica. 1929;4(1):51-64. doi: 10.1111/j.1600-0447.1929.tb03540
  6. Klekamp J. The Pathophysiology of Syringomyelia — Historical Overview and Current Concept. Acta Neurochir (Wien). 2002;144(7):649-664. doi: 10.1007/s00701-002-0944-3
  7. Klekamp J, Samii M. The Pathophysiology of Syringomyelia. Syringomyelia: Diagnosis and Treatment. Berlin: Springer; 2002;17-25. doi: 10.1007/978-3-642-56023-1_2
  8. Oldfield E, Muraszko K, Shawker T, Patronas N. Pathophysiology of syringomyelia associated with Chiari I malformation of the cerebellar tonsils. Journal of Neurosurgery. 1994;80(1):3-15. doi: 10.3171/jns.1994.80.1.0003
  9. Heiss J, Patronas N, DeVroom H, Shawker T, Ennis R, Kammerer W, Eidsath A, Talbot T, Morris J, Eskioglu E, Oldfield E. Elucidating the pathophysiology of syringomyelia. Journal of Neurosurgery. 1999;91(4):553-562. doi: 10.3171/jns.1999.91.4.0553
  10. Milhorat T, Capocelli A, Anzil A, Kotzen R, Milhorat R. Pathological basis of spinal cord cavitation in syringomyelia: analysis of 105 autopsy cases. Journal of Neurosurgery. 1995;82(5):802-812. doi: 10.3171/jns.1995.82.5.0802
  11. Milhorat T, Chou M, Trinidad E, Kula R, Mandell M, Wolpert C, Speer M. Chiari I Malformation Redefined: Clinical and Radiographic Findings for 364 Symptomatic Patients. Neurosurgery. 1999;44(5):1005-1017. doi: 10.1097/00006123-199905000-00042
  12. Tubbs R, Oakes W. The Chiari Malformations: A Historical Context. The Chiari Malformations. New York: Springer; 2013. doi: 10.1007/978-1-4614-6369-6_2
  13. Badie B, Mendoza D, Batzdorf U. Posterior Fossa Volume and Response to Suboccipital Decompression in Patients with Chiari I Malformation. Neurosurgery. 1995;37(2):214-218. doi: 10.1227/00006123-199508000-00004
  14. Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y. Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. Journal of Neurosurgery. 1997;86(1):40-47. doi: 10.3171/jns.1997.86.1.0040
  15. Bell W, Charney E, Bruce D, Sutton L, Schut L. Symptomatic Arnold-Chiari malformation: review of experience with 22 cases. Journal of Neurosurgery. 1987;66(6):812-816. doi: 10.3171/jns.1987.66.6.0812
  16. Taylor F, Larkins M. Headache and chiari i malformation: Clinical presentation, diagnosis, and controversies in management. Current Science Inc. 2002;6(4):331-337. doi: 10.1007/s11916-002-0056-z
  17. Pascual J, Oterino A, Berciano J. Headache in type I Chiari malformation. Neurology. 1992;42(8):1519-1519. doi: 10.1212/wnl.42.8.1519
  18. Sjaastad O, Fredriksen T, Pfaffenrath V. Cervicogenic Headache: Diagnostic Criteria. Headache. 1990;30(11):725-726. doi: 10.1111/j.1526-4610.1990.hed3011725.x
  19. Hwang G, Kim G, Jeong H, Sim Y, Park Y. Arnold Chiari I Malformation with Tip-Toe Gait: A Case Report. Korean J Spine. 2013;10(1):38. doi: 10.14245/kjs.2013.10.1.38
  20. Pollack I, Pang D, Kocoshis S, Putnam P. Neurogenic Dysphagia Resulting from Chiari Malformations. Neurosurgery. 1992;30(5):709-719. doi: 10.1227/00006123-199205000-00011
  21. Memarpour R, Tashtoush B, Issac L, Gonzalez-Ibarra F. Syringomyelia with Chiari I Malformation Presenting as Hip Charcot Arthropathy: A Case Report and Literature Review. Case Reports in Neurological Medicine. 2015;Article ID 487931:1-6. doi: 10.1155/2015/487931
  22. Klekamp J, Batzdorf U, Samii M, Bothe H. The surgical treatment of Chiari I malformation. Acta neurochir. 1996;138(7):788-801. doi: 10.1007/bf01411256
  23. Greenlee J, Donovan K, Hasan D, Menezes A. Chiari I Malformation in the Very Young Child: The Spectrum of Presentations and Experience in 31 Children Under Age 6 Years. PEDIATRICS. 2002;110(6):1212-1219. doi: 10.1542/peds.110.6.1212
  24. Arcaya J, Cacho J, Campo F, Grande J, Maillo A. Arnold-Chiari malformation associated with sleep apnea and central dysregulation of arterial pressure. Acta Neurologica Scandinavica. 1993;88(3):224-226. doi: 10.1111/j.1600-0404.1993.tb04222.x
  25. Keefover R, Sam M, Bodensteiner J, Nicholson A. Hypersomnolence and Pure Central Sleep Apnea Associated With the Chiari I Malformation. Journal of Child Neurology. 1995;10(1):65-67. doi: 10.1177/088307389501000116
  26. Alegre S, García-Rubira J, Patrignani G. Cardiac arrest in a 31-year-old man because of the Arnold-Chiari malformation. International Journal of Cardiology. 1994;46(3):286-288. doi: 10.1016/0167-5273(94)90253-4
  27. Selmi F, Davies K, Weeks R. Type I Chiari deformity presenting with profound sinus bradycardia: case report and literature review. British Journal of Neurosurgery. 1995;9(4):543-546. doi: 10.1080/02688699550041205
  28. James D. Significance of chronic tonsillar herniation in sudden death. Forensic Science International. 1995;75(2-3):217-223. doi: 10.1016/0379-0738(95)01786-0
  29. Faulhauer K, Loew K. The surgical treatment of syringomyelia. Long-term results. Acta neurochir. 1978;44(3-4):215-222. doi: 10.1007/bf01402063
  30. Sakushima K, Tsuboi S, Yabe I, Hida K, Terae S, Uehara R, Nakano I, Sasaki H. Nationwide survey on the epidemiology of syringomyelia in Japan. Journal of the Neurological Sciences. 2012;313(1-2):147-152. doi: 10.1016/j.jns.2011.08.045
  31. Aboulezz A, Sartor K, Geyer C, Gado M. Position of Cerebellar Tonsils in the Normal Population and in Patients with Chiari Malformation. Journal of Computer Assisted Tomography. 1985;9(6):1033-1036. doi: 10.1097/00004728-198511000-00005
  32. Meadows J, Kraut M, Guarnieri M, Haroun R, Carson B. Asymptomatic Chiari Type I malformations identified on magnetic resonance imaging. Journal of Neurosurgery. 2000;92(6):920-926. doi: 10.3171/jns.2000.92.6.0920
  33. Masur H, Oberwittler C, Reuther G, Heyen P. Cerebellar Herniation in Syringomyelia: Relation between Tonsillar Herniation and the Dimensions of the Syrinx and the Remaining Spinal Cord. European Neurology. 1995;35(3):162-167. doi: 10.1159/000117114
  34. Wang C, Wang X, Fu C, Wei L, Zhou D, Lin J. Analysis of cerebrospinal fluid flow dynamics and morphology in Chiari I malformation with cine phase-contrast magnetic resonance imaging. Acta Neurochir. 2014;156(4):707-713. doi: 10.1007/s00701-013-1958-8
  35. Batzdorf U, Khoo L, McArthur D. Observation on spine deformity and syringomyelia. Neurosurgery. 2007;61(2):370-378. doi: 10.1227/01.neu.0000279971.87437.1f
  36. Gardner W, Goodall, R. The Surgical Treatment of Arnold-Chiari Malformation in Adults. Journal of Neurosurgery. 1950;7(3):199-206. doi: 10.3171/jns.1950.7.3.0199
  37. Gardner W, Angel J. The Cause of Syringomyelia and its Surgical Treatment. Cleveland Clinic Journal of Medicine. 1958;25(1):4-8. doi: 10.3949/ccjm.25.1.4
  38. Bao C, Liu L, Wang B, Xia X, Gu Y, Li D, Zhan S, Chen G, Yang F. Craniocervical decompression with duraplasty and cerebellar tonsillectomy as treatment for Chiari malformation-I complicated with syringomyelia. Genetics and Molecular Research. 2015;14(1):952-960. doi: 10.4238/2015.february.3.2
  39. Quon J, Grant R, DiLuna M. Multimodal evaluation of CSF dynamics following extradural decompression for Chiari malformation Type I. Journal of Neurosurgery: Spine. 2015;22(6):622-630. doi: 10.3171/2014.10.spine1433
  40. Klekamp J. Surgical Treatment of Chiari I Malformation—Analysis of Intraoperative Findings, Complications, and Outcome for 371 Foramen Magnum Decompressions. Neurosurgery. 2012;71(2):365-380. doi: 10.1227/neu.0b013e31825c3426
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