Neurophysiological assessment of afferent-efferent interaction in the trigeminal-cervical system in patients with secondary headaches

Kuznetsova E.A.; Iakupov É.Z.

doi:https://doi.org/

Kuznetsova E.A.

Kafedra nevrologii, neĭrokhirurgii i meditsinskoĭ genetiki Kazanskogo gosudarstvennogo meditsinskogo universiteta

Iakupov É.Z.

Kafedra nevrologii, neĭrokhirurgii i meditsinskoĭ genetiki Kazanskogo gosudarstvennogo meditsinskogo universiteta

Neurophysiological assessment of afferent-efferent interaction in the trigeminal-cervical system in patients with secondary headaches

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Kuznetsova E.A., Iakupov É.Z.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(10): 54‑57

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To cite this article:

Kuznetsova EA, Iakupov ÉZ. Neurophysiological assessment of afferent-efferent interaction in the trigeminal-cervical system in patients with secondary headaches. S.S. Korsakov Journal of Neurology and Psychiatry. 2011;111(10):54‑57. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)

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Abstract:

We carried out the neurophysiological assessment of functional state of the trigeminal-cervical system and studied peculiarities of afferent-efferent interaction in patients with the most frequent variants of secondary headaches: chronic posttraumatic headaches, cervicogenic headaches, vascular headaches and painful dysfunction of temporomandibular articulation. According to the results of neurophysiological studies (somatosensory, trigeminal evoked potentials, blink reflex and stimulation EMG of masticatory muscles), the functional activity of the trigeminal system in patients with secondary headaches changes less significantly compared to patients with primary headaches. In most secondary headaches, the reflex activity of the trigeminal system and the EMG activity of masticatory muscles are determined by the functional state of spinal and brainstem structures.

Keywords:

trigeminal-cervical system

somatosensory evoked potentials

trigeminal evoked potentials

blink reflex

stimulation electromyography of masticatory muscles

chronic headache

posttraumatic headache

cervicogenic headache

vascular headache

painful dysfunction of temporomandibular articulation

Authors:

Kuznetsova E.A.

Kafedra nevrologii, neĭrokhirurgii i meditsinskoĭ genetiki Kazanskogo gosudarstvennogo meditsinskogo universiteta

Iakupov É.Z.

Kafedra nevrologii, neĭrokhirurgii i meditsinskoĭ genetiki Kazanskogo gosudarstvennogo meditsinskogo universiteta

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References:

Alekseev V.V., Kisel' S.A., Yakhno N.N. i dr. Tservikogennaya golovnaya bol': klinicheskaya kharakteristika, kriterii diagnoza. Bol' 2004; 2: 3: 20-27.
Alekseev V.V., Shekhter A.I., Skorobogatykh K.V., Shashkova E.V. Golovnye boli pri intrakranial'noi venoznoi disfunktsii. Bol' 2008; 3: 20: 15-21.
Gimranov R.F., Shchekut'ev G.A., Shabalov V.A., Kolyvanov M.V. Motornye otvety pri transkranial'noi magnitnoi stimulyatsii i somatosensornye vyzvannye potentsialy u bol'nykh s bolevymi sindromami. Voprosy neirokhirurgii 2001; 4: 19-22.
Gnezditskii V.V. Vyzvannye potentsialy mozga v klinicheskoi praktike. M: MEDpress-inform 2003; 264.
Zenkov L.R., Ronkin M.A. Funktsional'naya diagnostika nervnykh boleznei (Rukovodstvo dlya vrachei). 3-e izd., pererab. i dop. M: MEDpress-inform 2004; 488.
Ismagilov M.F., Yakupova A.A. Kliniko-elektromiograficheskaya kharakteristika golovnoi boli napryazheniya. Kazanskii meditsinskii zhurnal 1992; 92: 1: 44-46.
Kukushkin M.L., Khitrov N.K. Obshchaya patologiya boli. M: Meditsina 2004; 144.
Matkhalikov R.A., Skorobogatykh K.V. Nekotorye aspekty diagnostiki i patogeneza klasternoi golovnoi boli: obozrenie po materialam zhurnala "Cephalalgia" za 2004 g. Bol' 2005; 2: 7: 59-62.
Reshetnyak V.K., Kukushkin M.L. Bol': fiziologicheskie i patofiziologicheskie aspekty. Aktual'nye problemy patofiziologii: Izbrannye lektsii. Pod red. B.B. Moroza. M: Meditsina 2001; 354-389.
Toropina G.G. Somatosensornye vyzvannye potentsialy v issledovanii bolevykh sindromov. Bol' 2005; 1: 6: 2-8.
Ayzenberg I., Obermann M., Nyhuis P. et al. Central sensitization of the trigeminal and somatic nociceptive systems in medication overuse headache mainly involves cerebral supraspinal structures. Cephalalgia 2006; 26: 9: 1106-1114.
Dalessio D.J., Mclsaac H., Aung M., Polish J. Noninvasive trigeminal evoked potentials: normative data and application to neuralgia patients. Headache 1990; 30: 11: 696-700.
Di Clemente L., Coppola G., Magis D. et al. Nociceptive blink reflex and visual evoked potential habituations are correlated in migraine. Headache 2005; 45: 10: 1388-1413.
Firenze C., Del Gatto F., Mazzotta G., Gallai V. Somatosensory evoked potential study in headache patients. Cephalalgia 1988; 8: 3: 157-162.
Jaaskelainen S.K., Forssell H., Tenovuo O. Electrophysiological testing of the trigeminofacial system: aid in the diagnosis of atypical facial pain. Pain 1999; 80: 1-2: 191-200.
Nardone R., Tezzon F. The trigemino-cervical reflex in tension-type headache. Eur J Neurol 2003; 10: 3: 307-312.
Nardone R., Ausserer H., Bratti A. et al. Trigemino-cervical reflex abnormalities in patients with migraine and cluster headache. Headache 2008; 48: 4: 578-585.
Rossi P., Serrao M., Perrotta A. et al. Neurophysiological approach to central pain modulation in primary headaches. J of Headache and Pain 2005; 6: 4: 191-194.
Sand T., Zwart J.A. The blink reflex in chronic tension-type headache, migraine and cervicogenic headache. Cephalalgia 1994; 14: 447-450.
Serrao M., Perrotta A., Bartolo M. et al. Enhanced trigemino-cervical spinal reflex recovery cycle in pain-free migraineurs. Headache 2005; 45: 8: 1061-1068.
Soustiel J.F., Hafner H., Chistyakov A.V. et al. Trigeminal and auditory evoked responses in minor head injuries and post-concussion syndrome. Brain Inj 1995; 9: 8: 805-813.
Treede R.D. Neurophysiological studies of pain pathways in peripheral and central nervous system. J Neurol 2003; 250: 10: 1152-1161.
Truini A., Barbanti P., Galeotti F. et al. Trigeminal sensory pathway function in patient with SUNCT. Clin Neurophysiol 2006; 117: 8: 1821-1825.
van Vliet J.A., Vein A.A., Cessie S.L. et al. Impairment of trigeminal sensory pathways in cluster headache. Cephalgia 2003; 23: 6: 414-419.