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Korobtsov A.V.

Pacific State Medical University, Vladivostok, Russia

Kalinichenko S.G.

Pacific State Medical University, Vladivostok, Russia

The experimental strategies in the study of ischemic stroke

Authors:

Korobtsov A.V., Kalinichenko S.G.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(12‑2): 38‑44

DOI: 10.17116/jnevro201711712238-44

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Table of contents

THE EXPERIMENTAL STRATEGIES IN THE STUDY OF ISCHEMIC STROKE
THE EXPERIMENTAL STRATEGIES IN THE STUDY OF ISCHEMIC STROKE

To cite this article:

Korobtsov AV, Kalinichenko SG. The experimental strategies in the study of ischemic stroke. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(12‑2):38‑44. (In Russ.)
https://doi.org/10.17116/jnevro201711712238-44

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Использование инфографики авторами научных работ
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Abstract:

Literature data and own experience in the studies of experimental stroke methodology are reviewed. Advantages and disadvantages of the common models of focal ischemia used in the laboratory practice are discussed in details. The advantages of the filament occlusion of the middle cerebral artery in rats as the most adequate model of human stroke are substantiated. The authors suggest a modification of this variant using an additional coagulation of the pterygopalatine artery that allows the exclusion of the retrograde and collateral blood flow into the inner carotid artery after ligation of the common and external carotid arteries.

Keywords:

cerebral ischemia
experimental stroke
angio-architectonics
laboratory animals

Authors:

Korobtsov A.V.

Pacific State Medical University, Vladivostok, Russia

Kalinichenko S.G.

Pacific State Medical University, Vladivostok, Russia

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References:

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