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Fedorov A.A.

Urals State Medical University;
Yekaterinburg Medical Research Centre for Prophylaxis and Health Protection of Industrial Workers

Gaitova M.R.

Urals State Medical University;
City Clinical Hospital No. 40

Franc M.A.

Urals State Medical University

Telegina E.V.

Urals State Medical University

Dzyubinskaya E.V.

Lomonosov Moscow State University

Efimenko N.V.

North Caucasian Federal Scientific and Clinical Centre of the Federal Medical and Biological Agency

Chalaya E.N.

North Caucasian Federal Scientific and Clinical Centre of the Federal Medical and Biological Agency

Zhumanova E.N.

Petrovsky National Research Centre of Surgery

Moiseev V.V.

North Caucasian Federal Scientific and Clinical Centre of the Federal Medical and Biological Agency;
Sanatorium Villa Arnest

The long-term observation period of pregnant women after acute gestational pyelonephritis

Authors:

Fedorov A.A., Gaitova M.R., Franc M.A., Telegina E.V., Dzyubinskaya E.V., Efimenko N.V., Chalaya E.N., Zhumanova E.N., Moiseev V.V.

More about the authors

Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;101(6‑2): 33‑39

DOI: 10.17116/kurort202410106233

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Table of contents

THE LONG-TERM OBSERVATION PERIOD OF PREGNANT WOMEN AFTER ACUTE GESTATIONAL PYELONEPHRITIS
THE LONG-TERM OBSERVATION PERIOD OF PREGNANT WOMEN AFTER ACUTE GESTATIONAL PYELONEPHRITIS

To cite this article:

Fedorov AA, Gaitova MR, Franc MA, et al. . The long-term observation period of pregnant women after acute gestational pyelonephritis. Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;101(6‑2):33‑39. (In Russ.)
https://doi.org/10.17116/kurort202410106233

Подписка 2026 Вопросы курортологии, физиотерапии и лечебной физической культуры (Problems of Balneology, Physiotherapy and Exercise Therapy)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Abstract:

Urinary tract infections, in particular acute gestational pyelonephritis (AGP) determine a high risk of developing various complications of pregnancy and childbirth. The development of new medical technologies for the treatment of AGP remains relevant. It has not only high direct effectiveness, but also shows a distinct impact of secondary prevention of pyelonephritis exacerbations and a fetoprotective effect. An objective evidence for these effects is the study of long-term treatment outcomes.

OBJECTIVE

To evaluate the general condition of pregnant women in a randomized controlled study of the long-term observation period who underwent acute gestational pyelonephritis, birth results, quality of life of the patients and vitality of the newborns.

MATERIAL AND METHODS

The study included 93 women at the age of 16 to 40 years old who underwent AGP. They were divided into two groups by simple randomization: the main/MG (46 people) and the control/CG (47 people). The control group of the patients was prescribed the drug standard; the main one had intravenous ozone therapy (OT) in addition to it.

RESULTS

In the MG the patients had significant differences (p<0.05—0.001) with women of the CG in such indicators as: repeated relapses of gestational pyelonephritis (4.5 times), late gestational toxicosis (2.6 times), the number of newborns with normal growth and weight parameters (1.9 times), bacteriuria (3.0 times), leukocytouria (4.0 times), medical care for the main disease (5.0 times), outpatient treatment (8.0 times) and quality of life indicators — physical and social activity as well as general health.

CONCLUSION

An additional prescription in the standard of care for patients with AGP based on intravenous administration of an ozone-oxygen mixture significantly improves the long-term results of the therapy and the quality of life of patients who have undergone AGP, and also has a distinct fetoprotective effect. The absence of adverse reactions with all the patients including in the long-term follow-up period indicates the safety of a new complex of restorative treatment for AGP.

Keywords:

intravenous ozone therapy
acute gestational pyelonephritis
long-term treatment outcomes

Authors:

Fedorov A.A.

Urals State Medical University;
Yekaterinburg Medical Research Centre for Prophylaxis and Health Protection of Industrial Workers

Gaitova M.R.

Urals State Medical University;
City Clinical Hospital No. 40

Franc M.A.

Urals State Medical University

Telegina E.V.

Urals State Medical University

Dzyubinskaya E.V.

Lomonosov Moscow State University

Efimenko N.V.

North Caucasian Federal Scientific and Clinical Centre of the Federal Medical and Biological Agency

Chalaya E.N.

North Caucasian Federal Scientific and Clinical Centre of the Federal Medical and Biological Agency

Zhumanova E.N.

Petrovsky National Research Centre of Surgery

Moiseev V.V.

North Caucasian Federal Scientific and Clinical Centre of the Federal Medical and Biological Agency;
Sanatorium Villa Arnest

Received:

22.11.2024

Accepted:

24.12.2024

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