Pathophysiological mechanisms of the therapeutic action of alternating electromagnetic fields in the treatment of osteoarticular pathology

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Treatment of osteoarticular pathology with an alternating electromagnetic field (AEMF) is used today as a promising, non-invasive and safe strategy of physiotherapy. It has been shown that the action of alternating electromagnetic fields on the musculoskeletal system triggers signaling cascades that effectively contribute to the restoration of bone and articular tissue. The pathophysiological mechanisms underlying the cellular and subcellular effects of stimulation by an alternating electromagnetic field during the restoration of bone and articular tissue are considered. It was pointed out the several key signaling pathways involved in the restoration of bone and articular tissue under the influence of electromagnetic fields with an analysis of the potential for therapeutic application of electromagnetic fields alone or in combination with other available therapies.

Keywords:

alternating electromagnetic fields

signaling pathways

treatment of osteoarticular pathology

Authors:

Alekseeva L.I.

V.A. Nasonova Research Institute of Rheumatology

Byalovsky Yu.Yu.

Ryazan State Medical University

Zagorodniy N.V.

Peoples’ Friendship University of Russia

SPIN RSCI: 6889-8166
ORCID: 0000-0002-6736-9772

Ivanova G.E.

Karateev D.E.

M.F. Vladimirsky Moscow Regional Research Clinical Institute

Konchugova T.V.

National Medical Research Center for Rehabilitation and Balneology

SPIN RSCI: 3198-9797
ORCID: 0000-0003-0991-8988

Rakitina I.S.

Ryazan State Medical University

Strakhov M.A.

N.I. Pirogov Russian National Research Medical University

Received:

26.05.2021

Accepted:

27.05.2021

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