Features of innate immunity indicators in patients with recurrent exudative otitis media

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Kryukov A.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-0149-0676

Gankovskaya L.V.

Russian National Research Medical University named after N.I. Pirogov

Bondareva G.P.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

Kunelskaya N.L.

L. I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-1001-2609

Garov E.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0003-2473-3113

Nasaeva E.D.

Pirogov Russian National Research Medical University

Martirosyan T.G.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department

Features of innate immunity indicators in patients with recurrent exudative otitis media

Authors:

Kryukov A.I., Gankovskaya L.V., Bondareva G.P., Kunelskaya N.L., Garov E.V., Nasaeva E.D., Martirosyan T.G.

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Journal: Russian Bulletin of Otorhinolaryngology. 2023;88(1): 4‑9

DOI: 10.17116/otorino2022880114

Read: 1606 times

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To cite this article:

Kryukov AI, Gankovskaya LV, Bondareva GP, Kunelskaya NL, Garov EV, Nasaeva ED, Martirosyan TG. Features of innate immunity indicators in patients with recurrent exudative otitis media. Russian Bulletin of Otorhinolaryngology. 2023;88(1):4‑9. (In Russ.)
https://doi.org/10.17116/otorino2022880114

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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Abstract:

The article presents the features of the indicators of the innate immune response (TLR4, IL1B, TGFB, HBD1, and HBD2) in the exudate of the tympanic cavity in patients with recurrent exudative otitis media (EOM) with normal patency of the auditory tube and its dysfunction. The results of the study demonstrate changes in the indices of the innate immune response characteristic of the inflammatory process in patients with recurrent EOM against the background of dysfunction of the auditory tube in comparison with the group where it is absent. The data obtained can be used to clarify the pathogenesis of otitis media with dysfunction of the auditory tube, to develop new methods of diagnosis, prevention and therapy.

Keywords:

recurrent exudative otitis media

congenital immune response

Authors:

Kryukov A.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-0149-0676

Gankovskaya L.V.

Russian National Research Medical University named after N.I. Pirogov

Bondareva G.P.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

Kunelskaya N.L.

L. I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology;
Pirogov Russian National Research Medical University

ORCID: 0000-0002-1001-2609

Garov E.V.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0003-2473-3113

Nasaeva E.D.

Pirogov Russian National Research Medical University

Martirosyan T.G.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department

Received:

28.10.2022

Accepted:

13.12.2022

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