The state of the serotonin system in the patients presenting with chronic polypous rhinosinusitis

The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Search result: 0

Shishkin A.A.

Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990

Karakulova Iu.V.

Kafedra nevrologii lechebnogo fakul'teta im. prof. V.P. Pervushina Permskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. akad. E.A. Vagnera

Voronchikhina N.V.

Department of Otorhinolaryngology, Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990

The state of the serotonin system in the patients presenting with chronic polypous rhinosinusitis

Authors:

Shishkin A.A., Karakulova Iu.V., Voronchikhina N.V.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2017;82(6): 15‑17

DOI: 10.17116/otorino201782615-17

Read: 1533 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Shishkin AA, Karakulova IuV, Voronchikhina NV. The state of the serotonin system in the patients presenting with chronic polypous rhinosinusitis. Russian Bulletin of Otorhinolaryngology. 2017;82(6):15‑17. (In Russ.)
https://doi.org/10.17116/otorino201782615-17

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

Close metadata

Abstract:

This article presents the results of the study designed to determine the concentration of the neuromediator serotonin in the blood serum and tissue homogenates prepared from the polypous tissue harvested in the patients presenting with chronic polypous rhinosinusitis (CPR). The study included 51 patients with this pathology while 11 patients with chronic maxillary rhinosinusitis (CMR) and deflection of the nasal septum (DNS) made up the group of comparison. The serum serotonin levels were measured and compared in the patients of the main and both control groups. The results obtained give evidence of the significant inverse correlation between serotonin levels in the sera and tissue homogenates on the one hand and the history of allergic diseases in individual patients on the other hand.

Keywords:

chronic polypous rhinosinusitis

nasal breathing

serotonin

Authors:

Shishkin A.A.

Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990

Karakulova Iu.V.

Kafedra nevrologii lechebnogo fakul'teta im. prof. V.P. Pervushina Permskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. akad. E.A. Vagnera

Voronchikhina N.V.

Department of Otorhinolaryngology, Academician E.A. Vagner Perm State Medical University, Perm, Russia, 614990

Close metadata

References:

Bachert Zuberbier C, Klimek L, Khaltaev N. Die allergische Rhinitis und ihre Bedeutung für das Asthma: Update (ARIA 2008). Eine Bestandsaufnahme aus deutscher Sicht. Atemwegs und Lungenkrankheiten. 2008;34(6):23-240. https://doi.org/10.5414/atp34235
Arefyeva NA, Vishnyakov VV, Vakhrushev SG. Polipoznyj rinosinusit: klinicheskie rekomendacii. M. 2010. (In Russ.)
Cosway B, Tomkinson A, Owens D. The European positional paper on rhinosinusitis and nasal polyps: has the introduction of guidance on the management of sinus disease affected uptake of surgery and acute admissions for sinusitis? European Archives of Oto-Rhino-Laryngology. 2012;270(3):889-892. https://doi.org/10.1007/s00405-012-2027-2
Talley NJ, Locke GR, Lahr BD, et al. Functional dyspepsia, delayed gastric emptying, and impaired quality of life. Gut. 2006;55:933-939. https://doi.org/10.1136/gut.2005.078634
Ryazantsev SV, Artyushkina VK, Nacharov PV, Laptiyeva MA. The modern aspects of systemic corticosteroid therapy at patients with chronic polipozny rinosinusity. Rossijskaya Otorinolaringologiya 2013;2:114-121. (In Russ.)
Vinnikova NV. A microflora role in a pathogenesis of a chronic polipozny rinosinusit. Rossijskaya Otorinolaringologiya. 2015;1(74):34-37. (In Russ.)
Slominski A, Wortsman J. Neuroendocrinology of the skin. Endocrine Rev. 2000;21:457-487. https://doi.org/10.1210/er.21.5.457
Karakulova YuV. About pathogenetic mechanisms of formation of headaches of tension. Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. 2006;7:52-56. (In Russ.)
Kroeze WK, Kristiansen K, Roth BL. Molecular biology of serotonin receptors structure and function at the molecular level. Curr Top Med Chem. 2002;2(6):507-528. https://doi.org/10.2174/1568026023393796
Barkhatova VP. Neyrotransmittera and extrapyramidal pathology. M. 1988. (In Russ.)
Efimenko NA, Chernekhovskaya NE, Vyrenkov YuE. Rukovodstvo po klinicheskoj limfologi. M.: Polimag; 2001. (In Russ.)
Selyanina NV, Sumlivaya ON, Vorobyov NN, Karakulova YuV, Okishev MA. Serotonin of peripheral blood as marker of cerebral damages. Permskij medicinskij zhurnal, 2014;31(1):38-43. (In Russ.)
Ryazantsev SV. Mnogofaktornaja teorija jetiologii i patogeneza polipoza nosa i okolonosovyh pazuh. Zhurnal ushnyh, nosovyh, i gorlovyh boleznej. 1990;66:19-23. (In Russ.)

Log in to the site using your account in one of the services

Registration

Last Name

Name

Middle Name

E-mail

Phone

Address

Country

Zip

City

Region

Street

Home

Apartmen

Legal entity name

ИНН

КПП

Password

Password

Repeat password

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.