Characteristic of the microbiocenosis of the nasal mucous membrane in the patients presenting with acute bacterial rhinosinusitis

Kolenchukova O.A.

doi:https://doi.org/10.17116/otorino201782528-31

Kolenchukova O.A.

Research Institute of Medical Problems of the North, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russia, 660022

Characteristic of the microbiocenosis of the nasal mucous membrane in the patients presenting with acute bacterial rhinosinusitis

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Kolenchukova O.A.

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Journal: Russian Bulletin of Otorhinolaryngology. 2017;82(5): 28‑31

DOI: 10.17116/otorino201782528-31

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Kolenchukova OA. Characteristic of the microbiocenosis of the nasal mucous membrane in the patients presenting with acute bacterial rhinosinusitis. Russian Bulletin of Otorhinolaryngology. 2017;82(5):28‑31. (In Russ.)
https://doi.org/10.17116/otorino201782528-31

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

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Abstract:

The objective of the present work was to study the specific features of the microbiocenosis of the nasal mucous membrane in the patients presenting with acute bacterial rhinosinusitis (ABRS). We examined 86 patients with this condition at the age varying from 18 to 64 years. The control group consisted of practically healthy blood donors (n=156) registered at the Krasnoyarsk Regional Blood Centre №1; they were matched to the patients of the main study group in terms of the age and sex. In order to investigated bacterial flora of nasal mucosa from the standpoint of its role in the exacerbation of the disease, the microorganisms were cultured on the differential-diagnostic media. Their individual species were identified with the use of the conventional microbiological methods. They demonstrated the disturbances of the microbiocenosis of the nasal mucous membrane of the ABRS patients with the simultaneous increase of the total abundance of microorganisms regarded as potentially pathogenic ones. The study of pathogenic and persistent properties of the Staphylococcus strains isolated from the nasal mucosa of the patients suffering from acute bacterial rhinosinusitis, revealed the presence of practically all species supposed to be etiopathogenic agents able to produce the enzymes responsible for pathogenicity and persistence of the microorganisms. The results of the present study were interpreted as giving evidence of the disturbances of the microbiocenosis of the nasal mucosa resulting from the impairment of local immunity associated with trophic disorders in the mucous membrane of the nasal passages.

Keywords:

microflora

acute bacterial rhinosinusitis

nasal mucosa

pathogenic and persistence properties

Authors:

Kolenchukova O.A.

Research Institute of Medical Problems of the North, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russia, 660022

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References:

Baturo AP, Romanenko EE, Leonova AYu, Yartseva AS, Savlevich EL, Mokronosova MA. Domination of Staphylococcus aureus in microbiocenosis of nasal cavity in children and adults with infectious and allergic rhinitis. Zhurnal mikrobiologii, jepidemiologii i immunobiologii. 2015;1:72-74. (In Russ.)
Cope EK, Lynch SV. Novel microbiome-based therapeutics for chronic rhinosinusitis. Curr Allergy Asthma Rep. 2015;15(3):504. https://doi.org/10.1007/sll882-014-0504-y
Jain R, Douglas R. When and how should we treat biofilms in chronic sinusitis? Curr Opin Otolaryngol Head Neck Surg. 2014;22(l):16-21.https://doi.org/ https://doi.org/10.1097/MOO.0000000000000010
Mezentseva OYu, Medvedeva OA, Vorob’eva AA. The role of biofilms in pathogenesis of chronic bacterial rhinosinusitis. Vestnik otorinolaringologii. 2014;(2):79-81. (In Russ.)
Lazarevich IL, Kozlov VS. Acute rhinosinusitis: diagnostics and treatment. Vestnik otorinolaringologii. 2013;(5):88-92. (In Russ.)
Kolenchukova OA, Ignatova IA, Smirnova SV, Kapustina TA, Kin TI. Properties of nasal mucosal microflora in patients with allergic rhinosinusitis. Vestnik otorinolaringologii. 2008;(5):33-35. (In Russ.)
Lopatin AS, Ivanchenko OA, Soshnikov SS. Comparative study of the efficiency of different treatment regimens for chronic rhinosinusitis. Rossijskaya rinologiya. 2015;2:47-56. (In Russ.)
Zatoloka PА, Dotsenko ML. Microbiological state of mucous coat in the nasal cavity of hiv-infected patients. Immunopatologija, allergology a, infektologija. 2010;4:52-56. (In Russ.)
Chernich NM, Karnouchova OG. Microbial landscape of nasal cavity in patients with rhinitis symptoms in the setting of thyroid dysfunction. Rossijskaja otorinolaringologija. 2015;1:132-134. (In Russ.)
Рiskunov SZ. Reasons of growth of prevalence of diseases of the nose and nose bosoms. Rossijskaya rinologiya. 2009;17(2):1. (In Russ.)
Ovchinnikov AYu, Dzgenzgera GE, Lopatin AS. Acute bacterial sinusitis: in a search of rational antibacterial therapy. Rossijskaya rinologiya. 2009;17(2):4-7. (In Russ.)
Kamanin EI, Otvagin IV, Kozlov RS, Veselov AM. Acute bacterial rhinosinusitis. Klinicheskaja mikrobiologija i antimikrobnaja himioterapija. 2008;10(1):34-46. (In Russ.)
Piskunov SZ, Mezentseva OYu, Kalinkin AA. Bacterial rhinosinusitis and antibiotics. Rossijskaya rinologiya. 2011;19(1):36-41. (In Russ.)
Kolenchukova OA, Smirnova SV, Savchenko AA. Mikrobiocenoz slizistoj obolochki nosa i rinosinusity. Krasnojarsk: KRASGMU; 2011. (In Russ.)