Peculiar features of the coagulation, fibrinolytic, and anticoagulation systems of blood in the patients presenting with vascular ENT tumours

Antoniv T.V.; Efimochkina K.V.; Antoniv V.F.

doi:https://doi.org/

Antoniv T.V.

Kafedra otorinolaringologii Rossiĭskogo universiteta Druzhby narodov, Moskva

Efimochkina K.V.

Kafedra otorinolaringologii Rossiĭskogo universiteta Druzhby narodov, Moskva

Antoniv V.F.

Kafedra otorinolaringologii Rossiĭskogo universiteta Druzhby narodov, Moskva

Peculiar features of the coagulation, fibrinolytic, and anticoagulation systems of blood in the patients presenting with vascular ENT tumours

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Antoniv T.V., Efimochkina K.V., Antoniv V.F.

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Journal: Russian Bulletin of Otorhinolaryngology. 2014;(1): 17‑19

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Antoniv TV, Efimochkina KV, Antoniv VF. Peculiar features of the coagulation, fibrinolytic, and anticoagulation systems of blood in the patients presenting with vascular ENT tumours. Russian Bulletin of Otorhinolaryngology. 2014;(1):17‑19. (In Russ.)

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

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Abstract:

The objective of the present work was to study characteristics of the blood coagulation system in the patients presenting with vascular ENT tumours including the following parameters: a complete blood count, hemorrhage, coagulation, retraction, and blood clot lysis times. The patients with ENT hemangiomas experienced hypocoagulation in the preoperative period in combination with the predominance of the fibrinolytic processes and elevated levels of free heparin. These changes can be interpreted as a protective reaction to prevent intravascular coagulation in the case of the slow blood flow in hemangiomatous cavities. The results of the study indicate that the prophylactic administration of inhibitors of enhanced fibrinolysis in the preoperative period may be dangerous for the patients presenting with hemangiomas because suppression of this adaptive response prior to surgery is likely to promote massive microcoagulation under the influence of tissue thromboplastin.

Keywords:

vascular ENT tumours

hemangiomas

blood coagulation system

Authors:

Antoniv T.V.

Kafedra otorinolaringologii Rossiĭskogo universiteta Druzhby narodov, Moskva

Efimochkina K.V.

Kafedra otorinolaringologii Rossiĭskogo universiteta Druzhby narodov, Moskva

Antoniv V.F.

Kafedra otorinolaringologii Rossiĭskogo universiteta Druzhby narodov, Moskva

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References:

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