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Gurov A.V.

Kafedra otorinolaringologiiRNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Muzhichkova A.V.

Kafedra otorinolaringologii RNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii

Pharmacoepidemiological analysis of outpatient-based practice of antibacterial therapy of ENT organ infections

Authors:

Gurov A.V., Muzhichkova A.V.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2013;78(1): 77‑80

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To cite this article:

Gurov AV, Muzhichkova AV. Pharmacoepidemiological analysis of outpatient-based practice of antibacterial therapy of ENT organ infections. Russian Bulletin of Otorhinolaryngology. 2013;78(1):77‑80. (In Russ.)

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)
 
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The objective of the present study was to estimate the effectiveness of the antibacterial therapeutic regimen based at an outpatient facility. The data for statistical analysis were collected by examining 1542 patients presenting with infections of the upper pulmonary tract and ENT organs in 10 cities of the Russian Federation. It was shown that macrolides are most commonly used to treat the above infections whereas beta-lactams are prescribed significantly less frequently. The main pharmacodynamic and pharmacokinetic features of pharmaceuticals from the group of protected penicillins are described, and the rationale is provided for their application as the medicines of choice for the treatment of infections of the upper respiratory tract at the stage of outpatient-based medical care.

Keywords:

inflammatory diseases of ENT organs
antibacterial therapy
protected penicillins
drug resistance of microorganisms

Authors:

Gurov A.V.

Kafedra otorinolaringologiiRNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Muzhichkova A.V.

Kafedra otorinolaringologii RNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii

List of references:

  1. Kryukov A.I., Turovskii A.B. Antibakterial'naya terapiya ostrogo vospaleniya v otorinolaringologii. Spravochnik poliklinicheskogo vracha 2005; 3: 1: 76-77.
  2. Ball P., Baquero F., Cars O., File T., Garau J., Klugman K., Low E., Rubinstein E. Antibiotic therapy of community respiratory tract infections: strategies for optimal outcomes and minimized resistance emergence. J Antimicrob Chemother 2002; 49: 1: 31-40.
  3. Zhukhovitskii V.G. Obosnovanie ratsional'noi antibakterial'noi terapii v otorinolaringologii s pozitsii bakteriologa. Consilum medicum 2001; 3: 8: 362-370.
  4. Pal'chun V.T., Kunel'skaya N.L., Artem'ev M.E., Karabak V.I., Ogorodnikov D.S. Mikrobnyi peizazh i puti ratsional'noi antibiotikoterapii pri ostrykh gnoinykh zabolevaniyakh LOR-organov. Vestn otorinolar 2004; 5: 4-8.
  5. Kamanin E.I., Stetsyuk O.U. Infektsii verkhnikh dykhatel'nykh putei i LOR-organov. Prakticheskoe rukovodstvo po antiinfektsionnoi khimioterapii. Pod. red. L.S. Strachunskogo. M 2002.
  6. Strachunskii L.S., Kozlov S.N. Sovremennaya antimikrobnaya khimioterapiya. Rukovodstvo dlya vrachei. M: Borges 2002.
  7. Strachunskii L.S., Kamanin E.I. Antibakterial'naya terapiya infektsii v otorinolaringologii. Rus med zhurn 1998; 6: 11: 684-693.
  8. Kryukov A.I., Sedinkin A.A. Terapiya ostrogo bakterial'nogo verkhnechelyustnogo sinusita: issledovanie effektivnosti i bezopasnosti amoksitsillina/klavulanata. Spravochnik poliklinicheskogo vracha 2006; 4: 8: 91-93.
  9. White A.R., Kaue S., Poupard J., Pypstra R., Woodnutt G., Wynne B. Augmentin (amoxicillin/clavulanate) in the treatment of community-acquired respiratory tract infection: a review of the continuing development of an innovative antimicrobial agent. J Antimicrob Chemother 2004; 53: Suppl: 13-20.

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