A new technique for local immunotherapy of allergic rhinosinusitis - intranasal aerosol therapy with the use of a cycloferon solution

Tataurshchikova N.S.; Sidorovich I.G.

doi:https://doi.org/

Tataurshchikova N.S.

Laboratoriia biotekhnologii Instituta immunologii FMBA RF, Moskva

Sidorovich I.G.

Laboratoriia biotekhnologii Instituta immunologii FMBA RF, Moskva

A new technique for local immunotherapy of allergic rhinosinusitis - intranasal aerosol therapy with the use of a cycloferon solution

Authors:

Tataurshchikova N.S., Sidorovich I.G.

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Journal: Russian Bulletin of Otorhinolaryngology. 2012;77(2): 49‑52

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To cite this article:

Tataurshchikova NS, Sidorovich IG. A new technique for local immunotherapy of allergic rhinosinusitis - intranasal aerosol therapy with the use of a cycloferon solution. Russian Bulletin of Otorhinolaryngology. 2012;77(2):49‑52. (In Russ.)

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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Abstract:

The objective of this study was to estimate the clinical and immunological efficacy of local immunotherapy with the use of a cycloferon solution. The authors describe a new highly efficacious method for the treatment of allergic rhinosinusitis by means of the intranasal introduction of the cycloferon aerosol (125 mg/ml). A total of 79 patients presenting with this pathology were included in the study. Comparative evaluation of clinical and immunological efficiency of intranasal aerosol therapy using the cycloferon solution and its standard parenteral administration has demonstrated the high efficiency and safety of intranasal aerosol therapy in a group of immunocompromised patients with allergic rhinosinusitis. The study revealed correlation between clinical symptoms and characteristics of the patients' cytokine status which suggests the high informative value of measuring principle cytokine levels and especially their local fractions.

Keywords:

local immunotherapy

cytokine profile

immunocompromised patient

allergic rhinosinusitis

Authors:

Tataurshchikova N.S.

Laboratoriia biotekhnologii Instituta immunologii FMBA RF, Moskva

Sidorovich I.G.

Laboratoriia biotekhnologii Instituta immunologii FMBA RF, Moskva

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References:

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