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Isabekov R.S.

S.N. Fedorov National Medical Research Center “MINK “Eye Microsurgery”

Malyugin B.E.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”;
Russian University of Medicine

Gelyastanov A.M.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”

Gerasimov M.Yu.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”

Autologous oral mucosal epithelial transplantation in the treatment of bilateral limbal stem cell deficiency

Authors:

Isabekov R.S., Malyugin B.E., Gelyastanov A.M., Gerasimov M.Yu.

More about the authors

Journal: Russian Annals of Ophthalmology. 2025;141(4): 96‑101

DOI: 10.17116/oftalma202514104196

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Table of contents

AUTOLOGOUS ORAL MUCOSAL EPITHELIAL TRANSPLANTATION IN THE TREATMENT OF BILATERAL LIMBAL STEM CELL DEFICIENCY
AUTOLOGOUS ORAL MUCOSAL EPITHELIAL TRANSPLANTATION IN THE TREATMENT OF BILATERAL LIMBAL STEM CELL DEFICIENCY

To cite this article:

Isabekov RS, Malyugin BE, Gelyastanov AM, Gerasimov MYu. Autologous oral mucosal epithelial transplantation in the treatment of bilateral limbal stem cell deficiency. Russian Annals of Ophthalmology. 2025;141(4):96‑101. (In Russ.)
https://doi.org/10.17116/oftalma202514104196

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Short-term outcomes of corneal epithelial reco­nstruction in patients with bila­teral limbal stem cell defi­ciency using para­limbal oral muco­sal epithelial transplantation. Russian Annals of Ophthalmology. 2025;(5):54-65
Abstract:

This review analyzes Russian and international literature on the treatment of bilateral limbal stem cell deficiency (LSCD), focusing on the use of Simple Oral Mucosal Epithelial Transplantation (SOMET) as a surgical method for restoring the ocular surface. Contemporary sources report 64 cases of SOMET used in the treatment of bilateral LSCD: 35 cases of chemical burns, 16 of thermal burns, 7 cases of Stevens-Johnson syndrome, 1 keratitis, 1 cicatricial pemphigoid, 1 dermoid, 1 case of drug-induced LSCD (mitomycin C), etc. Notably, all transplantations resulted in complete epithelialization, and in 3 cases, penetrating keratoplasty was subsequently performed with favorable functional and anatomical outcomes.

Keywords:

bilateral limbal stem cell deficiency
limbal stem cell deficiency
labial mucosal epithelial transplantation
chemical burn

Authors:

Isabekov R.S.

S.N. Fedorov National Medical Research Center “MINK “Eye Microsurgery”

Malyugin B.E.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”;
Russian University of Medicine

Gelyastanov A.M.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”

Gerasimov M.Yu.

S.N. Fedorov National Medical Research Center “MNTK “Eye Microsurgery”

Received:

15.02.2025

Accepted:

13.03.2025

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References:

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