The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 101-59-87
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Neroyev V.V.

Moscow Helmholtz Research Institute of Eye Diseases, Moscow, Russia

Kiseleva T.N.

Department of Ultrasound of Helmholtz Moscow Research Institute of Eye Diseases, Moscow, Russia

Okhotsimskaia T.D.

FGBU Moskovskiĭ nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ im. Gel'mgol'tsa Minzdrava RF, Moskva

Eliseeva E.K.

Helmholtz National Medical Research Center of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062

Riabina M.V.

FGBU Moskovskiĭ nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ im. Gel'mgol'tsa Minzdrava RF, Moskva

Vasil'chenko V.V.

NII neĭrokhirurgii im. N.N. Burdenko, Moskva

Bilateral occlusion of retinal vessels in Waldenstrom’s disease (a case study)

Authors:

Neroyev V.V., Kiseleva T.N., Okhotsimskaia T.D., Eliseeva E.K., Riabina M.V., Vasil'chenko V.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(1): 90‑96

DOI: 10.17116/oftalma202013601190

Views: 1645

Downloaded: 47

Download PDF (RU)
Contact the author
Table of contents

To cite this article:

Neroyev VV, Kiseleva TN, Okhotsimskaia TD, Eliseeva EK, Riabina MV, Vasil'chenko VV. Bilateral occlusion of retinal vessels in Waldenstrom’s disease (a case study). Russian Annals of Ophthalmology. 2020;136(1):90‑96. (In Russ.)
https://doi.org/10.17116/oftalma202013601190

Подписка 2025 (Russian Annals of Ophthalmology)
 
МСФ на ЯМ
Close metadata
Recommended articles:
Surgical treatment of congenital and acquired inte­rnal caro­tid artery tortuosity in patients with ocular ischemic syndrome. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;(3):272-278

The article describes a clinical case of bilateral occlusion of retinal vessels in a patient with Waldenstrom’s disease – a rare lymphoplasmocytic tumor of the bone marrow characterized by a complex of syndromes, among which the syndrome of blood hyperviscosity dominates. Comprehensive clinical, instrumental and laboratory examinations revealed that besides the syndrome of blood hyperviscosity the patient also had loci of cerebral ischemia (according to magnetic resonance imaging), ocular hypoperfusion with severe deficiency of retinal and choroidal blood flow (according to Doppler methods) indicating the presence of ocular ischemic syndrome. Since bilateral occlusion of retinal vessels without concomitant vascular and/or systemic pathology is rare, patients with such diagnosis should be referred to a hematologist.

Keywords:

Waldenstrom’s disease
macroglobulinemia
occlusion of retinal vessels
hyperviscosity
ocular ischemic syndrome

Authors:

Neroyev V.V.

Moscow Helmholtz Research Institute of Eye Diseases, Moscow, Russia

Kiseleva T.N.

Department of Ultrasound of Helmholtz Moscow Research Institute of Eye Diseases, Moscow, Russia

Okhotsimskaia T.D.

FGBU Moskovskiĭ nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ im. Gel'mgol'tsa Minzdrava RF, Moskva

Eliseeva E.K.

Helmholtz National Medical Research Center of Eye Diseases, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062

Riabina M.V.

FGBU Moskovskiĭ nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ im. Gel'mgol'tsa Minzdrava RF, Moskva

Vasil'chenko V.V.

NII neĭrokhirurgii im. N.N. Burdenko, Moskva

List of references:

  1. Gertz MA, Fonseca R, Rajkumar SV. Waldenström’s macroglobulinemia. The Oncologist. 2000;5(1):63-67. https://doi.org/10.1634/theoncologist.5-1-63
  2. Kapoor P, Ansell SM, Fonseca R, Chanan-Khan A, Kyle RA, Kumar SK, Ailawadhi S. Diagnosis and management of Waldenström macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines. JAMA Oncology. 2017;3(9):1257-1265. https://doi.org/10.1001/jamaoncol.2016.5763
  3. Leblond V, Dimopoulos MA, Treon SP. Treatment Recommendations in Waldenström Macroglobulinemia. Waldenström’s Macroglobulinemia. 2017; 367-370. https://doi.org/10.1007/978-3-319-22584-5_26
  4. Gordeev IG, Soboleva VN, Volov NA, Mashykova Yu.M., Vishchipanova TE. Waldenstrom macroglobulinemia in the clinical practice of a physician – the difficulty of diagnosis. Terapevt. 2017;5:57-62. (In Russ.).
  5. Treon SP, Merlini G, Dimopoulos M. Waldenstrom’s Macroglobulinemia. Neoplastic Diseases of the Blood. 2018:617-638. https://doi.org/10.1007/978-3-319-25586-6_11
  6. Treon SP, Hunter Z, Aggarwal A, Ewen EP, Masota S, Lee C, Tournilhac O. Characterization of familial Waldenstrom’s macroglobulinemia. Annals of Oncology. 2005;17:488-494. https://doi.org/10.1093/annonc/mdj111
  7. Hunter ZR, Yang G, Xu L, Liu X Castillo JJ, Treon SP. Genomics, signaling, and treatment of Waldenström macroglobulinemia. Journal of Clinical Oncology. 2017;35(9):994-1001. https://doi.org/10.1200/jco.2016.71.0814
  8. Giordano T. Role of hepatitis C in Waldenstrom’s macroglobulinemia. Proceedings of the 5th International Workshop on Waldenstrom’s acroglobulinemia, Stockholm, Sweden 2008 (Abstract 117).
  9. Vasil’ev VI, Probatova NA, Tupicyn NN, Varlamova EY, Logvinenko OA, Kovrigina AM, Sholohova EN, Simonova MV, Safonova TN, Gorodetsky VR, Kokosadze NV, Pavlovskaya AM, Kondratjeva TN, Gayduk IV, Kadagidze ZG. Lymphoproliferative diseases in primary sjogren’s syndrome. Onkogematologiya. 2007;3:16-26. (In Russ.).
  10. Logvinenko OA, Vasil’ev VI. Association between Sjogren’s disease and lymphomas. Nauchno-prakticheskaya revmatologiya. 2006;(3):67-76. (In Russ.).
  11. Paiva B, Corchete LA, Vidriales MB, García-Sanz R, Perez JJ, Aires-Mejia I, Sarasquete ME. The cellular origin and malignant transformation of Waldenström macroglobulinemia Blood. 2015;125(15):2370-2380. https://doi.org/10.1182/blood-2014-09-602565
  12. Poulain S. Roumier C, Venet-Caillault A, Figeac M, Herbaux C, Marot G, Nibourel O. Genomic landscape of CXCR4 mutations in Waldenström macroglobulinemia. Clinical Cancer Research. 2016;22(6):1480-1488 https://doi.org/10.1158/1078-0432.ccr-15-0646
  13. Kozlovskaya LV, Rameev VV, Mrykhin NN, Kogarko IN, Kogarko BS Kidney injury associated with monoclonal gammopathies: Perspectives on diagnosis and treatment. Terapevticheskij arhiv (arhiv do 2018 g.). 2015;87(6):108-111. (In Russ.). https://doi.org/10.17116/terarkh2015876108-111
  14. Kim W, Kweon E. Hyperviscosity-related retinopathy in Waldenström’s macroglobulinemia. New England Journal of Medicine. 2016; 374 (1):73-73. https://doi.org/10.1056/nejmicm1501103
  15. Menke MN, Kweon E. Hyperviscosity-related retinopathy in Waldenström macroglobulinemia. Archives of ophthalmology. 2006;124(11):1601-1606. https://doi.org/10.1001/archopht.124.11.1601
  16. Alexander P, Flanagan D, Rege K, Foss A, Hingorani M. Bilateral simultaneous central retinal vein occlusion secondary to hyperviscosity in Waldenstrom’s macroglobulinaemia. Eye. 2008;22(8):1089-1092. https://doi.org/10.1038/eye.2008.193
  17. Merlini G, Baldini L, Broglia C, Comelli M, Goldaniga M, Palladini G, Gobbi PG. Prognostic factors in symptomatic Waldenstrom’s macroglobulinemia. Seminars in oncology. 2003;30(2):211-215. https://doi.org/10.1053/sonc.2003.50064
  18. Lee SE, Shin YU, Lim HW, Seong MC, Cho HY, Kang MH. Bilateral Simultaneous Central Retinal Vein Occlusion in a Patient with Waldenstrom’s Macroglobulinemia. Journal of the Korean Ophthalmological Society. 2016;57(6):1012-1017. https://doi.org/10.3341/jkos.2016.57.6.1012
  19. Li W, Chalam KV, Grover S. Bilateral Choroidal Detachment in Waldenström Macroglobulinemia. JAMA Ophthalmology. 2015;133(6):715-716. https://doi.org/10.1001/jamaophthalmol.2015.64
  20. Choi RY, Jacoby R, Shakoor A. Multimodality ocular imaging in a case report of hyperviscosity syndrome associated with lymphoplasmacytic leukemia: the images tell the story. Retinal cases & brief reports. 2019;13(3):238-240. https://doi.org/10.1097/icb.0000000000000565
  21. Lapsia S, Meyer R, Abazari A, Usmani K, Gathungu G. Bilateral Central Retinal Vein Occlusion in a patient with Ulcerative Colitis and Antiphospholipid Antibody Syndrome. Journal of pediatric gastroenterology and nutrition. 2016;62(3):25-26. https://doi.org/10.1097/mpg.0000000000000404
  22. Stone MJ, Bogen SA. Evidence-based focused review of management of hyperviscosity syndrome. Blood. 2012;119(10):2205-2208. https://doi.org/10.1182/blood-2011-04-347690

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register


We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.