Determination of the individual normal range of intraocular pressure in differential diagnosis between pseudonormal tension glaucoma and ischemic optic neuropathies

Mamikonian V.R.; Galoian N.S.; Sheremet N.L.; Kazarian É.É.; Shmeleva-Demir O.A.; Antonov A.A.; Tatevosian A.A.

doi:https://doi.org/

Mamikonian V.R.

Uchrezhdenie Rossiĭskoĭ akademii meditsinskikh nauk "NII glaznykh bolezneĭ RAMN", Moskva

Galoian N.S.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Sheremet N.L.

FGBU "NII glaznykh bolezneĭ" RAMN

Kazarian É.É.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

ORCID: 0000-0003-0391-4695

Shmeleva-Demir O.A.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Antonov A.A.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Tatevosian A.A.

Russian State Academy of Post-Diploma Education, Moscow

Determination of the individual normal range of intraocular pressure in differential diagnosis between pseudonormal tension glaucoma and ischemic optic neuropathies

Authors:

Mamikonian V.R., Galoian N.S., Sheremet N.L., Kazarian É.É., Shmeleva-Demir O.A., Antonov A.A., Tatevosian A.A.

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Journal: Russian Annals of Ophthalmology. 2014;130(4): 4‑7

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Mamikonian VR, Galoian NS, Sheremet NL, Kazarian ÉÉ, Shmeleva-Demir OA, Antonov AA, Tatevosian AA. Determination of the individual normal range of intraocular pressure in differential diagnosis between pseudonormal tension glaucoma and ischemic optic neuropathies. Russian Annals of Ophthalmology. 2014;130(4):4‑7. (In Russ.)

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)

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Abstract:

The study investigated the relation between the actual intraocular pressure (IOP) and its individual normal range in normal-tension glaucoma (NTG) and ischemic optic neuropathy (ION) outcome. A total of 39 patients (61 eyes) were examined. Group 1 included 19 patients (35 eyes) with newly diagnosed NTG, group 2 - 20 patients (26 eyes) with the ION outcome. Besides conventional tests, the ophthalmic assessment in all patients included determination of the individual normal range of IOP and evaluation of biomechanical properties of the cornea. It is showed that determination of the individual normal range of IOP may play a key role in confusing cases of differential diagnosis between NTG and ION. The average actual IOP in patients with NTG generally exceeds the individual normal range by 40% (more than 5 mmHg), whereas in patients with the ION outcome - by only 11.7% (less than 5 mmHg - buffer range). No statistically significant difference in IOP measurements by different tonometry methods was found in either NTG or ION patients with corneal compensated IOP less than 21 mmHg.

Keywords:

ocular blood flow volume

flowmetry

individual normal range of IOP

ischemic optic neuropathy

normal-tension glaucoma

Authors:

Mamikonian V.R.

Uchrezhdenie Rossiĭskoĭ akademii meditsinskikh nauk "NII glaznykh bolezneĭ RAMN", Moskva

Galoian N.S.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Sheremet N.L.

FGBU "NII glaznykh bolezneĭ" RAMN

Kazarian É.É.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

ORCID: 0000-0003-0391-4695

Shmeleva-Demir O.A.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Antonov A.A.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Tatevosian A.A.

Russian State Academy of Post-Diploma Education, Moscow

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