Impaired cardiac structural and functional parameters in patients with chronic heart failure and diabetic cardiac autonomic neuropathy

Statsenko M.E.; Turkina S.V.; Shalaeva S.S.; Vinnikova A.A.

doi:https://doi.org/

Statsenko M.E.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet

ORCID: 0000-0002-3306-0312

Turkina S.V.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdrava Rossii

Shalaeva S.S.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdrava Rossii

Vinnikova A.A.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdrava Rossii

Impaired cardiac structural and functional parameters in patients with chronic heart failure and diabetic cardiac autonomic neuropathy

Authors:

Statsenko M.E., Turkina S.V., Shalaeva S.S., Vinnikova A.A.

More about the authors

Journal: Therapeutic Archive. 2013;85(10): 23‑28

Read: 1631 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Statsenko ME, Turkina SV, Shalaeva SS, Vinnikova AA. Impaired cardiac structural and functional parameters in patients with chronic heart failure and diabetic cardiac autonomic neuropathy. Therapeutic Archive. 2013;85(10):23‑28. (In Russ.)

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Influence of the method of manual-physical correction on autonomic regulation in patients with essential arterial hypertension. Problems of Balneology, Physiotherapy and Exercise Therapy. 2024;(5):23-28

Validation of ballistocardiography data for predicting the sleep efficiency in healthy individuals and patients with insomnia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):60-66

Left ventricular myocardial performance index (Tei index) as an early marker of cardiotoxicity in antitumor therapy. Russian Cardiology Bulletin. 2024;(4-2):137-143

Correlation of motor symptoms and cardiovascular dysfunction in Parkinson’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(4):59-67

The role of neuroinflammation in the development of seizure activity and autonomic disorders in patients with epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(8):50-58

Pathogenetic aspects of the effects of changes in the geomagnetic field on the vegetative regulation and the risk of vascular disorders. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(9):145-150

Abstract:

Aim. To reveal the specific cardiac structural and functional features in patients with chronic heart failure (CHF) and diabetic cardiac autonomic neuropathy (CAN). Subjects and methods. Ninety patients aged 45-70 years with Functional Class II-III CHF in the early post-myocardial infarction period and with type 2 diabetes mellitus (DM2) were examined. A study group of 60 patients had signs of CAN (Group 1); a control group of 60 patients presented with CHF and DM2 without signs of CAN (Group 2). Results. The patients with CHF and DM2 with the manifestations of CAN were found to have higher left ventricular mass indices and greater QT dispersion than those with CHF and DM2 without CAN; there was a significant decrease in heart rate variability and a statistically significant preponderance of hypersympathicotonia. Conclusion. A clinically important relationship was found between cardiac autonomic dysregulation, CAN severity in patients with CHD and DM2 and cardiac structural and functional parameters.

Keywords:

cardiac structural and functional parameters

cardiac autonomic neuropathy

heart rate variability

Authors:

Statsenko M.E.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet

ORCID: 0000-0002-3306-0312

Turkina S.V.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdrava Rossii

Shalaeva S.S.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdrava Rossii

Vinnikova A.A.

Volgogradskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdrava Rossii

Close metadata

References:

Statsenko M.E., Turkina S.V., Shalaeva S.S. i dr. Novye vozmozhnosti medikamentoznoi korrektsii avtonomnoi kardial'noi neiropatii u bol'nykh sakharnym diabetom 2 tipa s khronicheskoi serdechnoi nedostatochnost'yu. Ros kardiol zhurn 2011; 5: 40-46.
Sokolov E.I. Diabeticheskoe serdtse. M: Meditsina 2002; 415.
Strongin A.G., Botova S.N., Pochinka I.G. Prognostiches-koe znachenie avtonomnoi kardial'noi neiropatii u patsientov s sochetaniem sakharnogo diabeta 2 tipa i khronicheskoi serdechnoi nedostatochnosti. Kardiologiya 2010; 2: 26-29.
Didangelos T.P., Arsos G.A., Karamitsos D.T. et al. Left ventricular systolic and diastolic function in normotensive type 1 diabetic patients with or without autonomic neuropathy: a radionuclide ventriculography study. Diabetes Care 2003; 26: 1955-1960.
Zola B., Kahn J., Juni J. et al. Abnormal cardiac function in diabetics with autonomic neuropathy in the absence of ischemic heart disease. J Clin Endocrinol Metab 1986; 63: 208-214.
Piya M.K., Shivu G.N., Tahrani A. et al. Abnormal left ventricular torsion and cardiac autonomic dysfunction in subjects with type 1 diabetes mellitus. Metabolism 2011; 8: 1115-1121.
Nishimura M., Hashimoto T., Kobayashi H. et al. Association between cardiovascular autonomic neuropathy and left ventricular hypertrophy in diabetic hemodialysis patients. Nephrol Dial Transplant 2004; 10: 325-328.
Algoritmy spetsializirovannoi pomoshchi bol'nym sakharnym diabetom. 5-i peresmotr. Sakharnyi diabet 2011; 3: 11.
American Diabetes Association and American Academy of Neurology: Report and recommendations of the San Antonio Conference on diabetic neuropathy (Consensus Statement). Diabetes 1988; 37: 1000-1004.
Ewing D.J., Campbell I.W., Murray H. et al. Immediate heart-rate response to standing: simple test for autonomic neuropathy in diabetes. Br Med J 1978; 1: 145-147.
Ewing D.J. Cardiac autonomic neuropathy in Diabetes and Heart Disease. Jarret R.J. (ed). Amsterdam, the Netherlands: Elsevier 1984: 99-132.
Natsional'nye Rekomendatsii VNOK i OSSN po diagnostike i lecheniyu KhSN (tretii peresmotr). M 2010; 112.
Konradi A.O., Zhukova A.V., Vinnik T.A. i dr. Strukturno-funktsional'nye parametry miokarda u bol'nykh gipertonicheskoi bolezn'yu v zavisimosti ot massy tela, tipa ozhireniya i sostoyaniya uglevodnogo obmena. Arterial'naya gipertenziya 2002; 8: 12-15.
Metodicheskie rekomendatsii po analizu variabel'nosti serdechnogo ritma pri ispol'zovanii razlichnykh ekhokardiograficheskikh sistem (analiz "korotkikh" zapisei). Pod red. R.M. Baevskogo. M 2001; 48.
Babunts I.V., Miridzhanyan E.M., Mashaekh Yu.A. Azbuka analiza variabel'nosti serdechnogo ritma. Stavropol': Printmaster 2002; 112.
Cosson S., Kevorkian J.P. Left ventricular diastolic dysfunction: an early sign of diabetic cardiomyopathy? Diabetes Metab 2003; 29: 455-466.
Boyer J.K., Thanigaraj Srihari, Schechtman Kenneth B. et al. Prevalence of ventricular diastolic dysfunction in asymptomatic, normotensive patients with diabetes mellitus. Am J Cardiol 2004; 7: 870-875.
Somaratne J.B., Whalley G.A., Poppe K.K. et al. Screening for left ventricular hypertrophy in patients with type 2 diabetes mellitus in the community. Cardiovasc Diabetol 2011; 10: 2-9.
Eguchi Kazuo, Boden-Albala Bernadette, Jin Zhezhen et al. Association Between Diabetes Mellitus and Left Ventricular Hypertrophy in a Multi-Ethnic Population. Am J Cardiol 2008; 12: 1787-1791.
Belenkov Yu.N., Mareev V.Yu., Ageev F.T. Khronicheskaya serdechnaya nedostatochnost'. Izbrannye lektsii po kardiologii. M: GEOTAR-Media 2006; 432.
Felício J.S., Santos F.M., ACCB de Souza et al. Autonomic neuropathy tests correlate with left ventricular mass and cardiac diastolic function in normotensive patients with type 2 diabetes mellitus and without left ventricular hypertrophy. Exp Clin Cardiol 2010; 15: 5-9.
Whitsel E.A., Raghunathan T.E., Pearce R.M. et al. RRinterval variation, the QT interval index and risk of primary cardiac arrest among patients without clinically recognized heart disease. Eur Heart J 2001; 22: 165-173.
Lunina E.Yu., Petrukhin I.S. Diagnosticheskaya tsennost' spektral'nogo analiza variabel'nosti serdechnogo ritma serdtsa dlya vyyavleniya kardial'noi avtonomnoi neiropatii pri sakharnom diabete 2 tipa. Ros kardiol zhurn 2012; 3: 42-46.
Mikhailov V.M. Variabel'nost' ritma serdtsa: opyt prakticheskogo primeneniya metoda. Ivanovo: Ivanovskaya gosudarstvennaya meditsinskaya akademiya 2002; 209.