Morphofunctional characteristic of the microvasculature of the lung tissue in acute fatal ethanol poisoning

Davydova Z.V.

Saint Petersburg State Pediatric Medical University

ORCID: 0000-0002-6673-8230

Yagmurov O.D.

Bureau of Forensic Medicine

ORCID: 0000-0002-8141-4488

Morphofunctional characteristic of the microvasculature of the lung tissue in acute fatal ethanol poisoning

Authors:

Davydova Z.V., Yagmurov O.D.

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Journal: Forensic Medical Expertise. 2020;63(4): 17‑21

DOI: 10.17116/sudmed20206304117

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Davydova ZV, Yagmurov OD. Morphofunctional characteristic of the microvasculature of the lung tissue in acute fatal ethanol poisoning. Forensic Medical Expertise. 2020;63(4):17‑21. (In Russ.)
https://doi.org/10.17116/sudmed20206304117

Подписка 2025-2 (Forensic Medical Expertise)

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The purpose of this work is an in-depth study of main morphological features and pathogenesis of acute lung injury in cases of acute fatal poisoning with ethanol; assessment of microcirculation disorders in the respiratory system; details of the mechanisms of development of non-cardiogenic pulmonary edema. An analysis of 160 deaths of men and women aged 19 to 85 years from acute ethanol poisoning was made. Histological preparations were colored with hematoxylin and eosin according to the Van Gieson method, elastic fibers — according to Weigert. It was established that the first reaction in response to the effect of ethanol is hemodynamic disorders, then interstitial and alveolar edema develops; pronounced changes occur in endothelial cells, which lead to plasmorrhagia and hyalinosis

Keywords:

toxic effects of ethanol

lung damage

morphological signs

Authors:

Davydova Z.V.

Saint Petersburg State Pediatric Medical University

ORCID: 0000-0002-6673-8230

Yagmurov O.D.

Bureau of Forensic Medicine

ORCID: 0000-0002-8141-4488

Received:

26.02.2020

Accepted:

23.03.2020

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