Morphofunctional characteristic of the microvasculature of the lung tissue in acute fatal ethanol poisoning

Davydova Z.V.; Yagmurov O.D.

doi:https://doi.org/10.17116/sudmed20206304117

Davydova Z.V.

St. Petersburg State Pediatric Medical University of Ministry of Health of Russia

Yagmurov O.D.

N.P. Bekhterev Institute of Human Brain of RAS

ORCID: 0000-0003-1822-6043

Morphofunctional characteristic of the microvasculature of the lung tissue in acute fatal ethanol poisoning

Authors:

Davydova Z.V., Yagmurov O.D.

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Journal: Forensic Medical Expertise. 2020;63(4): 17‑21

DOI: 10.17116/sudmed20206304117

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Davydova ZV, Yagmurov OD. Morphofunctional characteristic of the microvasculature of the lung tissue in acute fatal ethanol poisoning. Forensic Medical Expertise. 2020;63(4):17‑21. (In Russ.)
https://doi.org/10.17116/sudmed20206304117

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

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Abstract:

The purpose of this work is an in-depth study of main morphological features and pathogenesis of acute lung injury in cases of acute fatal poisoning with ethanol; assessment of microcirculation disorders in the respiratory system; details of the mechanisms of development of non-cardiogenic pulmonary edema. An analysis of 160 deaths of men and women aged 19 to 85 years from acute ethanol poisoning was made. Histological preparations were colored with hematoxylin and eosin according to the Van Gieson method, elastic fibers — according to Weigert. It was established that the first reaction in response to the effect of ethanol is hemodynamic disorders, then interstitial and alveolar edema develops; pronounced changes occur in endothelial cells, which lead to plasmorrhagia and hyalinosis

Keywords:

toxic effects of ethanol

lung damage

morphological signs

Authors:

Davydova Z.V.

St. Petersburg State Pediatric Medical University of Ministry of Health of Russia

Yagmurov O.D.

N.P. Bekhterev Institute of Human Brain of RAS

ORCID: 0000-0003-1822-6043

Received:

26.02.2020

Accepted:

23.03.2020

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References:

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