Morphofunctional vascular changes associated with sudden death in the young

Pigolkin Yu.I.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Dolzhansky O.V.

Petrovsky Russian Research Center for Surgery, Moscow, Russia

Reva G.V.

Department of Fundamental Medicine, Far Eastern Federal University, School of Biomedicine, Primorsky Krai, Russia, 690922

Shylova M.A.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Globa I.V.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Morphofunctional vascular changes associated with sudden death in the young

Authors:

Pigolkin Yu.I., Dolzhansky O.V., Reva G.V., Shylova M.A., Globa I.V.

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Journal: Forensic Medical Expertise. 2019;62(3): 9‑11

DOI: 10.17116/sudmed2019620319

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To cite this article:

Pigolkin YuI, Dolzhansky OV, Reva GV, Shylova MA, Globa IV. Morphofunctional vascular changes associated with sudden death in the young. Forensic Medical Expertise. 2019;62(3):9‑11. (In Russ.)
https://doi.org/10.17116/sudmed2019620319

Подписка 2025-2 (Forensic Medical Expertise)

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Diagnosis of sudden death in the young is based on the results of a set of research methods. Immunohistochemical, histochemical and histochemical methods are fundamental to the diagnosis of hidden forms of connective tissue pathology. These methods allow the sequence of initial and irreversible changes in connective tissue structures to be determined. The aim of this study was to determine the abnormalities of the vascular wall structure when using immunohistochemical and histological methods for the verification of congenital anomalies of various types of vessels, which expand the criteria for the diagnostic detection of individuals with connective tissue dysplasia. These investigation methods allow the diagnosis of hidden forms of congenital connective tissue pathology in the young. The main morphological signs of pathology of the aorta, carotid arteries, coronary and cerebral arteries are the disturbance of structural elements of the connective tissue.

Keywords:

connective tissue dysplasia

vascular abnormalities

hidden forms

Authors:

Pigolkin Yu.I.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Dolzhansky O.V.

Petrovsky Russian Research Center for Surgery, Moscow, Russia

Reva G.V.

Department of Fundamental Medicine, Far Eastern Federal University, School of Biomedicine, Primorsky Krai, Russia, 690922

Shylova M.A.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Globa I.V.

Sechenov’s First Moscow State Medical University, Moscow, Russia

List of references:

Pigolkin YuI, Shilova MA, Kil’dyushov EM, Gal’chikov YuI. Forensic medical characteristic of the causes behind sudden death in the young subjects. Sudebno-meditsinskaya ekspertiza. 2016;59(5):4-9. (In Russ.) https://doi.org/10.17116/sudmed20165954-9
Pigolkin YuI, Shilova MA, Zaharov SN, Boeva SE, Globa IV. Sudden death in cancer pathology forensic medical characteristics. Voprosi Onkologii. 2016;62(4):535-541. (In Russ.)
Kaktursky LV. Sudden cardiac death (clinical morphology). M: Meditsina dlya vsekh. 2000;127. (In Russ.)
Pigolkin YuI, Shilova MA, Globa IV. Vascular pathology in the aspect of sudden death in young adult sand connectivet issue dysplasia: anatomical, physiological, and morphological parallels. Angiologiya i sosudistaya khirurgiya. 2017;23(1):36-43. (In Russ.)
Dolzhansky OV, Shilova MA, Paltseva EM, Fedorov DN, Kocharyan EZ, Pigolkin YuI. Aortic aneurysm in Erdheim’s idiopathic cystic medialnecrosis in autopsy and forensic medical practice. Arhiv patologii. 2016;78(4):3-9. (In Russ.) https://doi.org/10.17116/patol20167843-9

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