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Golubev R.S.

Department of Toxicological Chemistry, Perm State Pharmaceutical Academy, Ministry of Health of the Russia, Perm, Russia, 614070

Lyust E.N.

Department of Toxicological Chemistry, Perm State Pharmaceutical Academy, Ministry of Health of the Russia, Perm, Russia, 614070

Malkova T.L.

Perm State Pharmaceutical Academy, Perm, Russia, 614070

The choice of the conditions for the preparation of the pregabalin samples from the biological fluids with the use of the liquid-liquid and solid phase extraction techniques

Authors:

Golubev R.S., Lyust E.N., Malkova T.L.

More about the authors

Journal: Forensic Medical Expertise. 2018;61(3): 40‑43

DOI: 10.17116/sudmed201861340-43

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Table of contents

THE CHOICE OF THE CONDITIONS FOR THE PREPARATION OF THE PREGABALIN SAMPLES FROM THE BIOLOGICAL FLUIDS WITH THE USE OF THE LIQUID-LIQUID AND SOLID PHASE EXTRACTION TECHNIQUES
THE CHOICE OF THE CONDITIONS FOR THE PREPARATION OF THE PREGABALIN SAMPLES FROM THE BIOLOGICAL FLUIDS WITH THE USE OF THE LIQUID-LIQUID AND SOLID PHASE EXTRACTION TECHNIQUES

To cite this article:

Golubev RS, Lyust EN, Malkova TL. The choice of the conditions for the preparation of the pregabalin samples from the biological fluids with the use of the liquid-liquid and solid phase extraction techniques. Forensic Medical Expertise. 2018;61(3):40‑43. (In Russ.)
https://doi.org/10.17116/sudmed201861340-43

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The objective of the present study was the development of the methods for the isolation and identification of pregabalin for the purpose of chemical toxicological analysis (CTA). The authors describe the methods used to obtain pregabalin from the model mixtures of urine and blood plasma with the use of liquid-liquid and solid phase extraction. In addition, a method for the quantitative determination of pregabalin by means of combined gas chromatography mass-spectrometry was applied.

Keywords:

pregabalin
chemical toxicological analysis
solid phase extraction
liquid-liquid extraction
combined gas chromatography mass-spectrometry

Authors:

Golubev R.S.

Department of Toxicological Chemistry, Perm State Pharmaceutical Academy, Ministry of Health of the Russia, Perm, Russia, 614070

Lyust E.N.

Department of Toxicological Chemistry, Perm State Pharmaceutical Academy, Ministry of Health of the Russia, Perm, Russia, 614070

Malkova T.L.

Perm State Pharmaceutical Academy, Perm, Russia, 614070

Close metadata

References:

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  13. Golubev RS, Lyust EN. Opredelenie pregabalina metodom gazovoi khromatografii s mass-spektrometricheskim detektirovaniem. V kn.: Sovremennye problemy razvitiya fundamental’nykh i prikladnykh nauk. II mezhdunarodnaya nauchno-prakticheskaya konferentsiya. Praga. 2016. (In Russ.)
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