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Pugacheva O.I.

GBOU VPO "Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii, Kursk, Rossiia, 305041

Astashkina A.P.

GBOU VPO "Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet"

Shormanov V.K.

Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet

Ostanin M.A.

GUZ Tul'skoĭ oblasti "Tul'skaia oblastnaia klinicheskaia bol'nitsa"

Specific features of the distribution of 2,4- and 2,6-dimethyl derivatives of hydroxybenzene in the body of the warm-blooded animals

Authors:

Pugacheva O.I., Astashkina A.P., Shormanov V.K., Ostanin M.A.

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Journal: Forensic Medical Expertise. 2014;57(4): 44‑48

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Table of contents

SPECIFIC FEATURES OF THE DISTRIBUTION OF 2,4- AND 2,6-DIMETHYL DERIVATIVES OF HYDROXYBENZENE IN THE BODY OF THE WARM-BLOODED ANIMALS
SPECIFIC FEATURES OF THE DISTRIBUTION OF 2,4- AND 2,6-DIMETHYL DERIVATIVES OF HYDROXYBENZENE IN THE BODY OF THE WARM-BLOODED ANIMALS

To cite this article:

Pugacheva OI, Astashkina AP, Shormanov VK, Ostanin MA. Specific features of the distribution of 2,4- and 2,6-dimethyl derivatives of hydroxybenzene in the body of the warm-blooded animals. Forensic Medical Expertise. 2014;57(4):44‑48. (In Russ.)

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)
МСФ на ЯМ
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Abstract:

This study was designed to elucidate the specific features of the distribution of 2,4- and 2,6-dimethyl derivatives of hydroxybenzene in the body of the warm-blooded animals (rats) after the intragastric administration of these poisonous substances. It was shown that large amounts of these compounds are present in the unmetabolized form in the blood and internal organs of the experimental animals. Their largest quantities were found in the stomach contents, spleen, and small intestines.

Keywords:

2,4-dimethyl hydroxybenzene
2,6-dimethyl hydroxybenzene
distribution
chemical and toxicological analysis

Authors:

Pugacheva O.I.

GBOU VPO "Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii, Kursk, Rossiia, 305041

Astashkina A.P.

GBOU VPO "Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet"

Shormanov V.K.

Kurskiĭ gosudarstvennyĭ meditsinskiĭ universitet

Ostanin M.A.

GUZ Tul'skoĭ oblasti "Tul'skaia oblastnaia klinicheskaia bol'nitsa"

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References:

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  4. Astashkina A.P., Shormanov V.K., Elizarova M.K. Ekstraktsiya 2,4-dimetilgidroxibenzola iz vodnykh rastvorov organicheskimi rastvoritelyami. Mezhdunarodnaya konferentsiya "Ekstraktsia organicheskikh soedineniy", 4-ya [Extraction of dimethylhydroxybenzene from the aqueous solutions with organic solvents. The 4th international conference "Extraction of organic substances"]. Voronezh 2010.
  5. Elizarova M.K. Khimiko-toksikologicheskoe issledovanie oksibenzola I ego monometil'nykh proizvodnykh: Avtoref. dis. … kand. pharm. nauk [The chemico-toxicological study of hydroxybenzene and its monomethyl derivatives: Synopsis of the thesis ... for candidate pharm. sci. degree]. Kursk 2004
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  8. Shormanov V.K., Gerasimov D.A., Siplivaya L.E. Sokhranyaemost' numesulida v trupnom material [The persistence of nimesulide in the cadaveric material]. Kursky nauchno-prakt vestn "Chelovek I ego zdorov'e" 2012; 3: 102-107.
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