The study of naphthyzin present in material evidence and biological fluids

Fedorov D.B.

Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia Minzdrava RF

Volchenko S.V.

Biuro sudebno-meditsinskoĭ ékspertizy Leningradskoĭ oblasti, Sankt-Peterburg

Novokshonova N.A.

Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia Minzdrava RF

Kuklin V.N.

Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia Minzdrava RF

The study of naphthyzin present in material evidence and biological fluids

Authors:

Fedorov D.B., Volchenko S.V., Novokshonova N.A., Kuklin V.N.

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Journal: Forensic Medical Expertise. 2013;56(5): 29‑33

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To cite this article:

Fedorov DB, Volchenko SV, Novokshonova NA, Kuklin VN. The study of naphthyzin present in material evidence and biological fluids. Forensic Medical Expertise. 2013;56(5):29‑33. (In Russ.)

Подписка 2025-2 (Forensic Medical Expertise)

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The optimal conditions for isolation of naphazoline from naphthyzin preparations and biological fluids with chloroform at pH 9.18 are described. The compound of interest was identified with the use of color and precipitation reactions, IR and UV spectroscopy, thin-layer and gas chromatography, and chemical methods including high performance liquid chromatography, chromatodensitometry, and UV spectroscopy. The results obtained by the three methods are comparable.

Keywords:

naphazoline isolation

identification

quantitative determination

Authors:

Fedorov D.B.

Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia Minzdrava RF

Volchenko S.V.

Biuro sudebno-meditsinskoĭ ékspertizy Leningradskoĭ oblasti, Sankt-Peterburg

Novokshonova N.A.

Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia Minzdrava RF

Kuklin V.N.

Sankt-Peterburgskaia gosudarstvennaia khimiko-farmatsevticheskaia akademiia Minzdrava RF

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