Study on effects of theraupetic and prophilactic toothpaste with NovaMin on oral cavity in young tobacco users

Elovikova T.M.

Ural State Medical University

Sablina S.N.

Ural State Medical University of the Ministry of Health of the Russian Federation

Ermishina E.Y.

Ural State Medical University of the Ministry of Health of the Russian Federation

Koshcheev A.S.

Ural Federal University named after the first President of Russia B. N. Yeltsin

Study on effects of theraupetic and prophilactic toothpaste with NovaMin on oral cavity in young tobacco users

Authors:

Elovikova T.M., Sablina S.N., Ermishina E.Y., Koshcheev A.S.

More about the authors

Journal: Stomatology. 2021;100(3): 35‑39

DOI: 10.17116/stomat202110003135

Downloaded: 27

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Elovikova TM, Sablina SN, Ermishina EY, Koshcheev AS. Study on effects of theraupetic and prophilactic toothpaste with NovaMin on oral cavity in young tobacco users. Stomatology. 2021;100(3):35‑39. (In Russ.)
https://doi.org/10.17116/stomat202110003135

Close metadata

THE AIM OF THE STUDY

Was to assess the clinical effectiveness of the course use of toothpaste with NovaMin by smoking and nonsmoking patients along with its complex effects on the oral cavity.

MATERIALS AND METHODS

75 young patients (46 males and 29 females, mean age 23.95±2.9 years) were divided into three groups of 25 individuals. The first group was composed of non-smoking patients using toothpaste with NovaMin. The second group (reference group) comprised patients using placebo toothpaste. The third group was composed of smoking patients using toothpaste with NovaMin. The clinical trials of patients included assessment of functional activity of minor salivary glands, the sialometric analysis, the study on microcrystallization of mixed saliva. The non-specific resistance of oral cavity was studied based on the analysis of absorption reaction of microorganisms by epithelial cells. All patients were questioned about the organoleptic characteristics of the toothpaste. The abovementioned features were assessed before the study, after the first use of the toothpaste, after day 7 and day 14.

RESULTS

The course use of toothpaste with NovaMin resulted in the plaque inhibiting effect (p≤0.05), increased functional activity of minor salivary glands (p≤0.05) promoting increased salivation and oral cavity cleansing. The concept of local recovery of the receptor apparatus of epithelial cells is confirmed for the first group of patients; the non-specific resistance in tobacco users is low, prevalence of Type I epithelial cells is defined (p≤0.05).

CONCLUSION

The evaluated toothpaste affects metabolism in the oral cavity because it was diagnosed that the non-specific resistance of the oral cavity and absorption by epithelia improved in all patients after the course use.

Keywords:

mixed saliva

microcrystallization

toothpaste

NovaMin

smokers

non-smoking patients

Authors:

Elovikova T.M.

Ural State Medical University

Sablina S.N.

Ural State Medical University of the Ministry of Health of the Russian Federation

Ermishina E.Y.

Ural State Medical University of the Ministry of Health of the Russian Federation

Koshcheev A.S.

Ural Federal University named after the first President of Russia B. N. Yeltsin

Received:

01.03.2021

Accepted:

13.04.2021

List of references:

Elovilova TM, Yermishima EYu, Koscheev AS, Prihodkina AS. Clinical and laboratory substantiation of application of treatment-and-prophylactic gel reducing toothpaste with sodium fluoride in young patients. Actual problems of dentistry. 2018;14(2):5-11. (In Russ.). https://doi.org/10.18481/2077-7566-2018-14-2-5-11
Elovilova TM, Karaseva VV, Sholudev SE, Skurikhina YaS, Mirsaev TD. Characteristics of parameters of oral homeostatic mechanisms in young tobacco smokers. Uralsky Meditsinsky Journal. 2020;9(192):44-48. (In Russ.). https://doi.org/10.25694/URMJ.2020.09.10
Karaseva VV, Elovikova TM, Koshcheev AS. Assessment of dental status, monitoring of individual hygiene and quality of life of patients with jaw defects in combination with medical osteonecrosis. Stomatology. 2020;99(5):80-86. (In Russ.). https://doi.org/10.17116/stomat20209905180
Kouzmina EM, Abdusalamova BF, Ravinskaya A. A. modern technologies of reducing teeth hypersensitivity. Dental Forum. 2016;2(5):15-21. (In Russ.).
Kouzmina EM, Kosicheva TA, Benja VN, Lapteva LI. Laboratory evaluation of impacts of 5% NovaMin toothpaste on obturation of dentinal canals. Dental forum. 2014;2(5):120-124. (In Russ.).
Molvinskikh V, Belokonova N, Elovicova T, Kiseleva D, Chervyakovskaya M, Antropova O, Olshvang O. Clinical and experimental substantiation of the choice of toothpastes on the basis of monitoring the composition of the oral fluid in the inhabitants of industrial areas. Actual Problems in Dentistry. 2019;15(1):33-37.
Orekhova LYu, Kuzmina EM, Kuzmina IN, Khamadeeva AM, Iordanishvili AK, Maslak EE. Consensus resolution on a modern view on the therapeutic and prophylactic effect of individual oral care products containing fluoride. Stomatology. 2019;98(4):29-33. (In Russ.). https://doi.org/10.17116/stomat20199804129
Osipova VA, Burdina PA. Comparative analysis of the effectiveness of the use of dental drugs to reduce tooth hyperesthesia. Uchenie Zapiski SPbGMU im. akad. I.P. Pavlova. 2020;27(2):57-62. (In Russ.). https://doi.org/10.24884/1607-4181-2020-27-2-57-62
Sablina SN, Grigoriev SS, Elovikova TM, Dorokhina KP, Koscheev AS, Gosteeva AV, Asadullaeva ZS. Special clinical aspects of stomatologic therapeutic problems in HIV-patients in hospital settings. Vestnik KGMA im. I.K. Akhunbaeva. 2020;2(3):118-128. (In Russ.).
Herman M, Golasik M, Piekoszewski W, Walas S, Napierala M, Wyganowska-Swiatkowska M, Kurhanska-Flisykowska A, et al. Essential and Toxic Metals in Oral Fluid-a Potential Role in the Diagnosis of Periodontal Diseases. Biological Trace Element Research. 2016;116(2):275-282.
Yaprak E, Yolcubal I, Sinanoğlu A, Doğrul-Demiray A, Guzeldemir-Akcakanat E, Marakoğlu I. High levels of heavy metal accumulation in dental calculus of smokers: a pilot inductively coupled plasma mass spectrometry study. Journal of Periodontal Research. 2016;52(2):83-88.
Grigoryan AS. Cytomorphometric study on the effect of smoking on tissues adjacent to dental implants. Stomatology. 2019;98(1):21-24. (In Russ.). https://doi.org/10.17116/stomat20199801121
Elovicova T, Karaseva V, Skurihina Ya, Koshchev A, Yepishova A. Evaluation of non-specific resistance of the oral mucosa in tobacco smokers. Actual Problems in Dentistry. 2020;16(1):30-34.
Elovicova T, Karaseva V, Molvinskikh V, Skurihina Ya, Koshchev A. Modeling of the express diagnostic method of the negative influence of smoking as a managed process in the practice of a dentist. Actual Problems in Dentistry. 2019;15(4):44-49.
Iordanishvili AK. Prevention of teeth hyperesis using domestic oral cavity care products. Meditsinsky Alphafit. 2019;23(3):8-12. (In Russ.). https://doi.org/10.33667/2078-5631-2019-3-23(398)-8-13
Iordanishvili AK, Orlov AK. Chemical composition of hard dental tissues in adults of different age groups with dental hyperesthesia. Institut Stomatologii. 2019;3(84):99-101. (In Russ.).
Arnold WH, Prange M, Naumova EA. Effectiveness of various toothpastes on dentine tubule occlusion. Journal of Dentistry. 2015;43(4):440-449.
Elovikova TM, Ermishima EYu, Mikheikina NI. Mechanisms of reparative action of a new repair and protect toothpaste. Stomatology. 2016;95(5):32-35. (In Russ.). https://doi.org/10.17116/stomat201695432-35
Elovikova TM, Ermishima EYu, Ssablina SN, Grigoriev SS, Koshcheev AS. Clinical and laboratorial research in physical-chemical characteristics of new toothpaste with hyaluron-ti forte complex. Actual Problems in Dentistry. 2020;16(4):46-50. (In Russ.). https://doi.org/10.18481/2077-7566-20-16-4-46-50
Elovilova TM, Ermishima EYu, Uvarova LV, Koshcheev AS. The increased sensitivity of dentin: the mechanisms of remineralization using toothpaste with tin fluoride. Stomatology. 2019;98(5):66-71. (In Russ.). https://doi.org/10.17116/stomat20199805166

Close metadata