Evaluation of effectiveness of a mouthwash containing antiseptic octenidine dihydrochloride

Sabanceva E.G.; Dmitrieva N.A.; Avramenko E.A.; Ivanova E.V.; Ezhova E.G.; Pochivalin V.P.

doi:https://doi.org/10.17116/stomat202110002132

Sabanceva E.G.

Russian Medical Academy of Continuing Education

Dmitrieva N.A.

National Medical Research Center for Therapy and Preventive Medicine

Avramenko E.A.

Dental clinic «Intelldent»

Ivanova E.V.

Institute for Cellular and Intracellular Symbiosis of Ural Division of RAS

ORCID: 0000-0002-4974-8947

Ezhova E.G.

Russian Medical Academy of Continuing Education

Pochivalin V.P.

Russian Medical Academy of Continuing Education

Evaluation of effectiveness of a mouthwash containing antiseptic octenidine dihydrochloride

Authors:

Sabanceva E.G., Dmitrieva N.A., Avramenko E.A., Ivanova E.V., Ezhova E.G., Pochivalin V.P.

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Journal: Stomatology. 2021;100(2): 32‑39

DOI: 10.17116/stomat202110002132

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To cite this article:

Sabanceva EG, Dmitrieva NA, Avramenko EA, Ivanova EV, Ezhova EG, Pochivalin VP. Evaluation of effectiveness of a mouthwash containing antiseptic octenidine dihydrochloride. Stomatology. 2021;100(2):32‑39. (In Russ.)
https://doi.org/10.17116/stomat202110002132

Подписка 2026 Стоматология (Stomatology)

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Abstract:

THE AIM OF THE STUDY

Was to assess changes in the oral microbiota when using octenidine dihydrochloride mouthwash.

MATERIALS AND METHODS

Quantitative and qualitative changes in the oral microbiota were studied and evaluated after a single rinse, course application and long-term dates.

RESULTS

A single rinse resulted in a significant decrease in the number of pathogenic microorganisms: S. aureus, C. albicans, and Enterobacteriae. After a seven-day course of mouthwash application, the complete disappearance of pathogenic microorganisms: S. aureus, S. albicans, and Enterobacteriae and an increase in the number of Lactobacillus spp were revealed. 7 days after the mouthwash was canceled, there was some recovery of pathogenic (S. aureus, Candida), the number of Lactobacillus spp. remained the same, normal microflora almost completely restored.

CONCLUSION

Octenidine dihydrochloride mouthwash may be recommended for wide use in dental practice in the treatment of various oral pathological conditions, including candidiasis and dysbiosis.

Keywords:

octenidine dihydrochloride

oral microbiota

oral dysbiosis

Authors:

Sabanceva E.G.

Russian Medical Academy of Continuing Education

Dmitrieva N.A.

National Medical Research Center for Therapy and Preventive Medicine

Avramenko E.A.

Dental clinic «Intelldent»

Ivanova E.V.

Institute for Cellular and Intracellular Symbiosis of Ural Division of RAS

ORCID: 0000-0002-4974-8947

Ezhova E.G.

Russian Medical Academy of Continuing Education

Pochivalin V.P.

Russian Medical Academy of Continuing Education

Received:

13.03.2020

Accepted:

15.05.2020

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References:

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