Oxytocin is widely used in obstetric practice to induce and augment labor, to stop atonic postpartum hemorrhage, and to enhance lactation. However, there are a number of restrictions on oxytocin use. Therefore, there is an active quest for oxytocin receptor agonists. The paper gives information on synthetic peptide oxytocin analogues, among which carbetocin is most promising, particularly in combating atonic uterine bleeding. It also presents data on plant oxytocin analogues, including kalata B1 and other cyclotides. They were discovered originally in the study of plants growing in Africa (sub-Saharan areas), the decoctions of which are used in folk medicine in Africa to induce and augment labor and to combat atonic bleeding. There are data on the uterostimulants contained in pomegranate (Punica granatum L.) seeds, in the edible portion of pineapple (Ananas comosus), and in fir (Abies sibírica) needle extract, as well as on first-generation non-peptide oxytocin analogues, such as WAY-267464 that is able to pass through the blood-brain barrier and to activate oxytocin receptors in the neurons of the emotional brain.