Immunity system disorders play a considerable role in the pathogenesis of many diseases, including gynecological ones. The anti-pathogenic drugs, the therapeutic effects of which occur by regulating the pathological processes via physiological mechanisms in the body, are being used more and more now. The specific feature of cytokine therapy is its impact on the pathogenesis of different diseases. Local cytokine therapy enhances the efficiency of combination treatment, by normalizing a local immune response, reducing the magnitude of an inflammatory response, and improving reparative processes. Combination therapy using prolonged local cytokine therapy with superlymph promotes higher cure rates and lower recurrence rates.