Thirty pregnant women with mild and moderate gestosis and fetoplacental insufficiency with first-to-second degree uterine-placental circulatory impairment were examined. The authors studied the parameters of fetometry, Doppler study of placental blood flow, and hemorheology at baseline and during combination therapy with diosmin (phlebodia 600) and actovegin for a month. All the pregnant women received combined antihypertensive therapy with bisoprolol in a daily dose of 2.5-5 mg and slow-release nifedipine in a daily dose of 30 mg. Placental blood flow parameters became normal; fetoplacental insufficiency compensation was achieved; and baseline abnormal blood rheological and viscosity properties were corrected.