This study was undertaken to improve the results of treatment for chronic pelvic pain in women with chronic nonspecific salphingo-oophoritis and chronic cystitis. Ninety-one reproductive-age women with pelvic pain were examined. The examination demonstrated the significant detection rate of inflammatory diseases of internal genitals, urinary bladder, and locomotor apparatus and pelvic venous plethora. Chronic pelvic pain in the women was noted to be accompanied by impaired autonomic balance, increased activity of regulatory systems, and psychoemotional disorders, in whose pattern there was a preponderance of anxiety and depressive disorders. The detected disorders were found to affect the most important correlates of quality of life. Hemodynamic and microcirculatory disorders and abnormal pelvic muscle structures were shown to be of importance in the development of pain syndrome. To treat this category of patients, the author developed a comprehensive program using preformed physical factors and therapeutic exercises, the implementation of which could reduce the duration of treatment and the rate of relapses of pain syndrome and dysuria and achieve persistent remission.