Efficiency of use of selective dopamine (D2) receptor agonists for the prevention of ovarian hyperstimulation syndrome

Ashkharua T.A.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Krasnopol'skaia K.V.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii;
kafedra akusherstva i ginekologii FUV MONIKI im. M.F. Vladimirskogo

SPIN RSCI: 1252-3811
Scopus AuthorID: 57370972700

Manannikova T.N.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Efficiency of use of selective dopamine (D2) receptor agonists for the prevention of ovarian hyperstimulation syndrome

Authors:

Ashkharua T.A., Krasnopol'skaia K.V., Manannikova T.N.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2011;11(4): 67‑72

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To cite this article:

Ashkharua TA, Krasnopol'skaia KV, Manannikova TN. Efficiency of use of selective dopamine (D2) receptor agonists for the prevention of ovarian hyperstimulation syndrome. Russian Bulletin of Obstetrician-Gynecologist. 2011;11(4):67‑72. (In Russ.)

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The paper presents the results of use of stimulated in-vitro fertilization cycles in 45 patients with more than 20 growing follicles, who received human chorionic gonadotropin (hCG), 5000 IU, as an ovulation trigger and dopamine (D2) receptor agonists (cabergoline) for the prevention of ovarian hyperstimulation syndrome (OHSS); in 94 patients with less than or equal to 20 growing follicles, who took hCG, 10 000 IU, as an ovarian trigger, and in 47 patients with more than 20 growing follicles who used hCG, 5000 IU, as an ovarian trigger. Cabergoline was demonstrated to be able to significantly reduce the incidence of early OHSS in patients with a verified hyperergic response of the follicular apparatus to gonadotropins without its negative effect on the probability of the occurrence of pregnancy and its course in the first trimester.

Keywords:

dopamine (D2) receptor agonists

cabergoline

ovarian hyperstimulation syndrome

Authors:

Ashkharua T.A.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Krasnopol'skaia K.V.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii;
kafedra akusherstva i ginekologii FUV MONIKI im. M.F. Vladimirskogo

SPIN RSCI: 1252-3811
Scopus AuthorID: 57370972700

Manannikova T.N.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

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