Application of pelargonium extract in complicated course of acute respiratory infection of the upper airways

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Treatment of acute respiratory infection (ARI), which in most cases has a viral etiology, is a challenging and ultimately unresolved task. Despite the availability of clinical guidelines (international and national), a wide range of existing means and methods of treatment, ARI is often the cause of unjustified prescription of antibiotics, which contributes to the increase of the selection tempo and spread of resistant strains of microorganisms in the populations, the frequency of adverse reactions that occur in a patient during treatment. In addition, the inflammatory process in ARI is often characterized by a complicated course that has a significant impact on the outcome of the disease. Therefore, the development of rational approaches to ARI treatment remains a topical area of clinical research.

OBJECTIVE

To analyze and summarize data on the therapeutic effectiveness of extract from the roots of Pelargonium sidoides (pelargonium) in ARI.

MATERIAL AND METHODS

The publications (articles and related abstracts) presented in the PubMed database were used. The choice of material was carried out according to the following keywords: cold, acute respiratory viral infection, diagnosis of acute sinusitis, phytotherapy of acute sinusitis, Pelargonium sidoides.

RESULTS AND CONCLUSION

The analysis of published results of clinical studies indicates the relevance of inclusion of the extract from the roots of Pelargonium sidoides in the ARI treatment protocols. The high safety profile and clinically significant effectiveness of this drug application allow it to be considered as an important component of comprehensive pharmacological therapy of ARI.

Keywords:

cold

acute respiratory viral infection

diagnosis of acute sinusitis

phytotherapy of acute sinusitis

Pelargonium sidoides

pelargonium extract

Authors:

Nosulya E.V.

L.I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-3897-8384

Kim I.A.

Pirogov Russian National Research Medical University;
National Medical Research Center for Otorhinolaryngology of the Federal Medical-Biological Agency

ORCID: 0000-0003-1078-6388

Luchsheva Yu.V.

L.I. Sverzhevsky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-8412-710X

Yushkina M.A.

Pirogov Russian National Research Medical University

ORCID: 0000-0002-9823-1047

Received:

08.07.2024

Accepted:

20.07.2024

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