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Sevostyanova E.V.

Federal Research Center for Fundamental and Translational Medicine

Nikolaev Yu.A.

Federal Research Centre for Fundamental and Translational Medicine

Mitrofanov I.M.

Federal Research Center for Fundamental and Translational Medicine

Polyakov V.Ya.

Federal Research Center for Fundamental and Translational Medicine

Selyatitskaya V.G.

Federal Research Centre for Fundamental and Translational Medicine

Regional, gender, and age-specific features of polymorbidity in residents of the Novosibirsk region and the Republic of Sakha (Yakutia)

Authors:

Sevostyanova E.V., Nikolaev Yu.A., Mitrofanov I.M., Polyakov V.Ya., Selyatitskaya V.G.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2023;26(5): 63‑70

DOI: 10.17116/profmed20232605163

Read: 1171 times

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Table of contents

REGIONAL, GENDER, AND AGE-SPECIFIC FEATURES OF POLYMORBIDITY IN RESIDENTS OF THE NOVOSIBIRSK REGION AND THE REPUBLIC OF SAKHA (YAKUTIA)
REGIONAL, GENDER, AND AGE-SPECIFIC FEATURES OF POLYMORBIDITY IN RESIDENTS OF THE NOVOSIBIRSK REGION AND THE REPUBLIC OF SAKHA (YAKUTIA)

To cite this article:

Sevostyanova EV, Nikolaev YuA, Mitrofanov IM, Polyakov VYa, Selyatitskaya VG. Regional, gender, and age-specific features of polymorbidity in residents of the Novosibirsk region and the Republic of Sakha (Yakutia). Russian Journal of Preventive Medicine. 2023;26(5):63‑70. (In Russ.)
https://doi.org/10.17116/profmed20232605163

 
Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Polymorbidity (PM) is associated with increased hospitalization, disability, and mortality of patients, indicating the need to study PM in different populations.

OBJECTIVE

To study regional, gender, and age-specific PM features in residents of the Novosibirsk region (NR) and the Republic of Sakha (Yakutia).

MATERIAL AND METHODS

A retrospective single-center observational study of patients with medical conditions (a total of 26.671 subjects, including 10.495 males and 16.176 females) over the age of 18 years was conducted at the clinic of the Federal Research Centre for Fundamental and Translational Medicine (Novosibirsk) from 2003 to 2020. The study included 22.667 residents of the Novosibirsk region (NR) and 4.004 residents of the Republic of Sakha (Yakutia). The study used the archival method based on the data from medical records, considering all identified diagnoses in each patient as clinical entities and classes of the International Classification of Diseases of the 10th Revision (ICD-10). The PM was assessed by the number of ICD-10 classes in one patient. All patients were divided into subgroups depending on the region of residence, gender, and age.

RESULTS

It was found that the residents of Yakutia had a higher PM compared to the NR residents. This pattern was observed among males of adolescence and the second mature age periods and females of all ages, except for adolescence. The gender features of the PM were revealed, with higher rates of PM in the NR residents, young males, and females in the second mature and elderly age periods; in the residents of Yakutia females in all age periods, except for adolescence. Age-related PM features were revealed, with increased rates with increasing age.

CONCLUSION

Identified features of polymorbidity determine the need to consider the region of residence, gender, and age of patients to improve the prevention, diagnosis, and treatment system.

Keywords:

polymorbidity
regional features
gender
age periods

Authors:

Sevostyanova E.V.

Federal Research Center for Fundamental and Translational Medicine

Nikolaev Yu.A.

Federal Research Centre for Fundamental and Translational Medicine

Mitrofanov I.M.

Federal Research Center for Fundamental and Translational Medicine

Polyakov V.Ya.

Federal Research Center for Fundamental and Translational Medicine

Selyatitskaya V.G.

Federal Research Centre for Fundamental and Translational Medicine

Received:

21.11.2022

Accepted:

20.01.2023

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References:

  1. Tarlovskaya EI. Comorbidity and polymorbidity — a modern interpretation and urgent tasks facing the therapeutic community. Kardiologiya. 2018;58(9S): 29-38. (In Russ.). https://doi.org/10.18087/cardio.2562
  2. Willadsen TG, Siersma V, Nicolaisdóttir DR, Køster-Rasmussen R, Jarbøl DE, Reventlow S, Mercer S.W, Olivarius NF. Multimorbidity and mortality: A 15-year longitudinal registry-based nationwide Danish population study. Journal of Comorbidity. 2018;14;8(1):2235042X18804063. https://doi.org/10.1177/26335565221122025
  3. Wey MY, Mukamal KJ. Multimorbidity, mortality and long-term physical functioning in 3 prospective cohorts of community-dwelling adults. American Journal of Epidemiology. 2018;187:103-112.  https://doi.org/10.1093/aje/kwx198
  4. Wetterling T. Pathogenesis of multimorbidity — what is known? Zeitschrift fur Gerontologie und Geriatrie. 2021;54(6):590-596.  https://doi.org/10.1007/s00391-020-01752-z
  5. Gorbanev SA, Fedorov VN, Tihonova NA. On the state and improvement of the management of sanitary and epidemiological well-being in the Arctic zone of the Russian Federation. Ekologiya cheloveka. 2019;10:4-14. (In Russ.). https://doi.org/10.33396/1728-0869-2019-10-4-14
  6. Kovshov AA, Novikova YUA, Fedorov VN, Tihonova NA. Socio-economic portrait and medical and demographic characteristics of the Arctic territories of the Republic of Sakha (Yakutia). Rossijskaya Arktika. 2021;13:105-117. (In Russ.). https://doi.org/10.24412/2658-4255-2021-2-105-117
  7. Korchin VI, Korchina TYA, Ternikova EM, Bikbulatova LN, Lapenko VV. Influence of climatic and geographical factors of the Yamalo-Nenets Autonomous Okrug on the health of the population (review). Zhurnal mediko-biologicheskih issledovanij. 2021;9(1):77-88. (In Russ.). https://doi.org/10.37482/2687-1491-Z046
  8. Mitrofanov IM, Nikolaev YUA, Dolgova NA, Pospelova TI. Regional features of polymorbidity in the modern clinic of internal diseases. Klinicheskaya medicina. 2013;6:26-29. (In Russ.).
  9. Hrisanfova EN, Perevozchikov IV. Antropologiya. 3-e izd. M.: Izd-vo Moskovskogo universiteta: Nauka; 2002. (In Russ.).
  10. Speranskij VS, Nikolenko VN, Anisimova EA, Aristova IS, Zagorovskaya TM. Lekcii po medicinskoj antropologii. 2-e izd. Saratov: Izdatel`stvo Saratovskogo medicinskogo uiversiteta; 2008. (In Russ.).
  11. Hasnulin VI, Voevoda MI, Hasnulin PV, Artamonova OG. Modern view on the problem of arterial hypertension in subpolar and arctic regions. Literature review. Ekologiya cheloveka. 2016;3:43-51. (In Russ.). https://doi.org/10.33396/1728-0869-2016-3-43-51
  12. Kaznacheev VP. Mechanisms of human adaptation in high latitudes. L.: Medicina; 1980. (In Russ.).
  13. Hasnulin VI, Hasnulin PV. Modern concepts of the mechanisms forming northern stress in humans in high latitudes. Ekologiya cheloveka. 2012;1:3-11. (In Russ.). https://doi.org/10.17816/humeco17512
  14. Gudkov AB, Popova ON, Neobuchennyh AA, Bogdanov MYu. Ecological and physiological characteristics of the Arctic climatic factors. Literature review. Morskaya medicina. 2017;3(1):7-13. (In Russ.). https://doi.org/10.22328/2413-5747-2017-3-1-7-13
  15. Ul’yanovskaya SA, Bazhenov DV, Shestakova VG, Kalinkin MN. Influence of climatic and geographical factors of the North on the adaptive responses of the human body. Patologicheskaya fiziologiya i e`ksperimental`naya terapiya. 2020;64(1):147-154. (In Russ.). https://doi.org/10.25557/0031-2991.2020.01.147-154
  16. Verizhnikova LN, Aryamkina OL, Terent’eva NN. Somatic pathology in residents of the Khanty-Mansiysk Autonomous Okrug — Ugra. Byulleten’ sibirskoj mediciny. 2020;19(2):13-19. (In Russ.).
  17. Panin LE. Homeostasis and problems of circumpolar medicine (methodological aspects of adaptation). Byulleten’ Sibirskogo otdeleniya Rossiyskoy Akademii medicinskih nauk. 2010;3:6-11. (In Russ.).
  18. Selyatickaya VG. Glucocorticoid hormones: from the processes of adaptation to the environmental factors of the North to metabolic disorders in diabetes. Byulleten’ Sibirskogo otdeleniya Rossiyskoy Akademii medicinskih nauk. 2012;32(1):13-20. (In Russ.).
  19. Roberts KC, Rao D, Bennett TL, Loukine L, Jayaraman GC. Prevalence and patterns of chronic disease multimorbidity and associated determinants in Canada. Health Promotion and Chronic Disease Prevention in Canada: Research, Policy and Practice. 2015;35(6):87-94.  https://doi.org/10.24095/hpcdp.35.6.01
  20. Liu J, Ma J, Wang J, Zeng DD, Song H, Wang L. Comorbidity analysis according to sex and age in hypertension patients in China. International Journal of Medical Sciences. 2016;13(2):99-107.  https://doi.org/10.7150/ijms.13456
  21. Lazebnik LB. Formation of polymorbidity in society. Klinicheskaya gerontologiya. 2015;21(3-4):3-7. (In Russ.).
  22. Yarnall AJ, Sayer AA, Clegg A, Rockwood K, Parker S, Hindle JV. New horizons in multimorbidity in older adults. Age and Ageing. 2017;46(6):882-888.  https://doi.org/10.1093/ageing/afx150
  23. Barnes PJ. Mechanisms of development of multimorbidity in the elderly. European Respiratory Journal 2015;45(3):790-806.  https://doi.org/10.1183/09031936.00229714
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