Locomotor disorders that are noted by specialists in the students of many universities in Russia are 15 to 42.5% of all health problems in the students. These diseases limit their professional choice and can cause disability. The timely detection of joint mobility disorders makes it possible to start preventive measures in time and to prevent the possible development of degenerative diseases. Objective — to investigate joint mobility in apparently healthy young people and to identify mobility differences according to gender and the dominant hand. Material and methods. The investigation enrolled 18—22-year-old students who had no locomotor complaints. The joint range of motion was measured by means of a goniometer on both active and passive motion. The findings were processed using a package of Statistica 10.0 applied programs. Results. A total of 100 students (67 women and 33 men) were examined. It was found that according to almost all parameters, joint mobility was more common in the women than in the men, which could be explained by sexual anatomical and physiological differences in the locomotor system. Joint mobility was established to be greater in the non-dominant hand than in the dominant one, which was attributable to the degree of muscle tonus. The elbow angle as an integral goniometric indicator of the upper limb reflects better the differences in the mobility of the dominant and non-dominant hands, which may judge that there is a predisposition to degenerative diseases of the upper limb joints. Conclusion. Impaired mobility of the joint suggests that its biomechanics and normal functioning may be disordered. Timely detection of these disorders allows for proper prevention of degenerative joint diseases.