Сomparative  evaluation of sperm DNA fragmentation and other sperm parameters

Zhabin S.G.; Trechenkov E.A.; Artifeksov S.B.; Pavlenko I.I.; Polukarov A.N.

doi:https://doi.org/10.17116/repro2015214121-124

Zhabin S.G.

МБЛПУ «Зональный перинатальный центр» (дир. — к.м.н. А.Н. Полукаров), Новокузнецк, Россия, 654007, ФБУЗ «Приволжский окружной медицинский центр» (дир. — С.В. Романов) Федерального медико-биологического агентства России, Нижний Новгород, Россия

Trechenkov E.A.

Artifeksov S.B.

Pavlenko I.I.

Polukarov A.N.

Zonal'nyĭ perinatal'nyĭ tsentr, Novokuznetsk

Сomparative evaluation of sperm DNA fragmentation and other sperm parameters

Authors:

Zhabin S.G., Trechenkov E.A., Artifeksov S.B., Pavlenko I.I., Polukarov A.N.

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Journal: Russian Journal of Human Reproduction. 2015;21(4): 121‑124

DOI: 10.17116/repro2015214121-124

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To cite this article:

Zhabin SG, Trechenkov EA, Artifeksov SB, Pavlenko II, Polukarov AN. Сomparative evaluation of sperm DNA fragmentation and other sperm parameters. Russian Journal of Human Reproduction. 2015;21(4):121‑124. (In Russ.)
https://doi.org/10.17116/repro2015214121-124

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

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Abstract:

Objective. To determine the correlation between sperm DNA fragmentation, acrosome reaction, sperm motility, and other semen parameters. Material and methods. Semen samples from 56 infertility patients were analyzed according to WHO guidelines. Sperm DNA damage was assessed by sperm chromatin desertion test (Halosperm). Intensity of acrosome reaction was determined by ionophore challenge. Results. A significant negative correlation between progressive sperm motility and DNA fragmentation was indicated. Only moderate correlation has been established between the percentage of morphologically normal spermatozoa and the sperm DNA fragmentation index. Sperm DNA damage was not correlated with the results of acrosome reaction assay and the antispermal antibodies test. Conclusion. Thus, an increased risk of sperm DNA damage is associated with low sperm motility and abnormal sperm morphology, but not with induced acrosome reaction.

Keywords:

sperm DNA fragmentation

semen analysis

acrosome reaction

Kruger’s index