Objectives. To identify the relationships of follicular hormones and growth factors with IVF outcome in patients with endocrine infertility. Method. Follicular fluid (FF) collected from 169 follicles at different developmental stages from hyperandrogenic patients (n=65), patients with hyperprolactinemia (n=59) and woman with regular cycle (n=45) undergoing IVF.  Results. We found few statistically significant correlation of FF hormones and growth factors with IVF outcomes. For control group: E2 level was correlated to normal fertilization rate (r=-0.39), EGF was correlated to embryo number (r=0.33). For patients with hyperprolactinemia: IGF-1 and testosterone were correlated to normal fertilization rate (r=0.35, r=-0.28 respectively), EGF to embryo number (r=-0.35), TGF- and endothelin-1 to implantation rate (r=-0.15, r=-0.31 respectively),TGF- to implantation rate (r=-0.15). For hyperandrogenic women: bFGF and TGF- were correlated to cumulative embryo score (Gardner) (r=0.56; r=0.82 respectively), endotelin-1 was correlated to implantation rate (r=-0.56). Conclusion. We have identified several regulatory molecules that were related to normal and pathological stages of folliculogenesis (Е2 and EGF for normal folliculogenesis; IGF-1, EGF, testosterone, TGF-, endothelin-1, for hyperprolactinemia; bFGF, TGF-, endothelin-1 - for women with hyperandrogegism).