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Ratushnyi M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Polyakov A.P.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia;
I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Rebrikova I.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Reshetov I.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Kravtsov S.A.

City Clinical Oncological Hospital No. 1

Mordovsky A.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Andreeva Yu.Yu.

Russian Medical Academy of Continuous Professional Education

Visceral flaps for oral cavity reconstruction and prevention of xerostomia in cancer patients: a case series and morphological study

Authors:

Ratushnyi M.V., Polyakov A.P., Rebrikova I.V., Reshetov I.V., Kravtsov S.A., Mordovsky A.V., Andreeva Yu.Yu.

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Journal: Plastic Surgery and Aesthetic Medicine. 2023;(2): 5‑16

DOI: 10.17116/plast.hirurgia20230215

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Downloaded: 49

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Table of contents

To cite this article:

Ratushnyi MV, Polyakov AP, Rebrikova IV, Reshetov IV, Kravtsov SA, Mordovsky AV, Andreeva YuYu. Visceral flaps for oral cavity reconstruction and prevention of xerostomia in cancer patients: a case series and morphological study. Plastic Surgery and Aesthetic Medicine. 2023;(2):5‑16. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia20230215

 
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OBJECTIVE

To improve treatment outcomes in patients with oral cavity cancers via postoperative reconstruction using visceral flaps.

MATERIAL AND METHODS

We present clinical cases of microsurgical reconstruction of oral cavity using free gastro-omental, jejunum and colonic flaps after resection of malignancies. We performed biopsy of colonic mucous fragment in 10 patients and gastric mucosa in 14 patients at various times after reconstruction.

RESULTS

Visceral flaps allow restoring oral cavity with morphotypical tissue that has optimal plasticity, thickness and adaptation to the edges of defect. These flaps do not cause sensations of a foreign body, changes in taste and do not require pre-prosthetic preparation. Intestine and gastric fragments release a secret providing additional moisture to the oral cavity and preventing xerostomia after radiotherapy. Histological analysis of colon and gastric fragments revealed that transplantation into environment of oral cavity with another enzymatic and acid-base composition leads to moderate atrophy without obvious inflammatory infiltration of mucosal base or severe dysplasia.

CONCLUSION

Autotransplantation of visceral tissues allows restoring oral mucosa by similar morphological tissue and improving the results of social and functional rehabilitation of patients with oral cavity tumors.

Keywords:

oral cavity defects
visceral flap
xerostomia

Authors:

Ratushnyi M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Polyakov A.P.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia;
I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Rebrikova I.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Reshetov I.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Kravtsov S.A.

City Clinical Oncological Hospital No. 1

Mordovsky A.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Andreeva Yu.Yu.

Russian Medical Academy of Continuous Professional Education

Received:

23.10.2022

Accepted:

15.12.2022

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