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Ratushnyi M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Polyakov A.P.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia;
I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Rebrikova I.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Reshetov I.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Kravtsov S.A.

City Clinical Oncological Hospital No. 1

Mordovsky A.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Andreeva Yu.Yu.

Russian Medical Academy of Continuous Professional Education

Visceral flaps for oral cavity reconstruction and prevention of xerostomia in cancer patients: a case series and morphological study

Authors:

Ratushnyi M.V., Polyakov A.P., Rebrikova I.V., Reshetov I.V., Kravtsov S.A., Mordovsky A.V., Andreeva Yu.Yu.

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2023;(2): 5‑16

DOI: 10.17116/plast.hirurgia20230215

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Table of contents

VISCERAL FLAPS FOR ORAL CAVITY RECONSTRUCTION AND PREVENTION OF XEROSTOMIA IN CANCER PATIENTS: A CASE SERIES AND MORPHOLOGICAL STUDY
VISCERAL FLAPS FOR ORAL CAVITY RECONSTRUCTION AND PREVENTION OF XEROSTOMIA IN CANCER PATIENTS: A CASE SERIES AND MORPHOLOGICAL STUDY

To cite this article:

Ratushnyi MV, Polyakov AP, Rebrikova IV, Reshetov IV, Kravtsov SA, Mordovsky AV, Andreeva YuYu. Visceral flaps for oral cavity reconstruction and prevention of xerostomia in cancer patients: a case series and morphological study. Plastic Surgery and Aesthetic Medicine. 2023;(2):5‑16. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia20230215

Подписка 2026 Пластическая хирургия и эстетическая медицина (Plastic Surgery and Aesthetic Medicine)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

OBJECTIVE

To improve treatment outcomes in patients with oral cavity cancers via postoperative reconstruction using visceral flaps.

MATERIAL AND METHODS

We present clinical cases of microsurgical reconstruction of oral cavity using free gastro-omental, jejunum and colonic flaps after resection of malignancies. We performed biopsy of colonic mucous fragment in 10 patients and gastric mucosa in 14 patients at various times after reconstruction.

RESULTS

Visceral flaps allow restoring oral cavity with morphotypical tissue that has optimal plasticity, thickness and adaptation to the edges of defect. These flaps do not cause sensations of a foreign body, changes in taste and do not require pre-prosthetic preparation. Intestine and gastric fragments release a secret providing additional moisture to the oral cavity and preventing xerostomia after radiotherapy. Histological analysis of colon and gastric fragments revealed that transplantation into environment of oral cavity with another enzymatic and acid-base composition leads to moderate atrophy without obvious inflammatory infiltration of mucosal base or severe dysplasia.

CONCLUSION

Autotransplantation of visceral tissues allows restoring oral mucosa by similar morphological tissue and improving the results of social and functional rehabilitation of patients with oral cavity tumors.

Keywords:

oral cavity defects
visceral flap
xerostomia

Authors:

Ratushnyi M.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Polyakov A.P.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia;
I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Rebrikova I.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Reshetov I.V.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Health of Russia

Kravtsov S.A.

City Clinical Oncological Hospital No. 1

Mordovsky A.V.

Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Andreeva Yu.Yu.

Russian Medical Academy of Continuous Professional Education

Received:

23.10.2022

Accepted:

15.12.2022

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References:

  1. Sostoyanie onkologicheskoj pomoshchi naseleniyu Rossii v 2020 godu. Kaprin AD, Starinsky VV, Shakhzadova AO, eds. M: MNIOI im. P.A. Gertsena — filial FGBU «NMITs radiologii» Minzdrava Rossii; 2021:239. (In Russ.).
  2. Komanduri SK, Hormuzdi D, Desai SS, et al. Free Gastric Flap for Oral Reconstruction — a Feasibility Study in Oral Defects. Indian J Surg Oncol. 2021;12(1):172-176.  https://doi.org/10.1007/s13193-020-01276-3
  3. Patel UA, Hartig GK, Hanasono MM, et al. Locoregional Flaps for Oral Cavity Reconstruction: A Review of Modern Options. Otolaryngol Head Neck Surg. 2017;157(2):201-209.  https://doi.org/10.1177/0194599817700582
  4. Karpenko AV, Sibgatullin RR, Boyko AA, et al. The infrahyoid musculocutaneous flap for the oral cavity reconstruction. Zlokachestvennye opukholi. 2016;1(17):36-43. (In Russ.). https://doi.org/10.18027/2224-5057-2016-1-36-43
  5. Kovalenko NV, Nenarokomov AYu, Ivanov AI, Tolstopyatov SE, Zhavoronkova VV, Chukhnin AG, Speransky DL, Devyatchenko TF. Submental Myodermal Flap in Buccal Reconstruction after Extended Combined Resection. Creative Surgery and Oncology. 2021;11(2):132-137. (In Russ.). https://doi.org/10.24060/2076-3093-2021-11-2-132-137
  6. Deganello A, Gitti G, Parrinello G, et al. Cost analysis in oral cavity and oropharyngeal reconstructions with microvascular and pedicled flaps. Acta Otorhinolaryngol Ital. 2013;33(6):380-387. PMID: 24376293; PMCID: PMC3870449.
  7. Post SF, Werker PMN, Dijkstra PU. Microsurgical Reconstruction of the Oral Cavity with Free Flaps from the Anterolateral Thigh and Radial Forearm: Example of Confounding by Indication? Ann Surg Oncol. 2017;24(Suppl 3):640.  https://doi.org/10.1245/s10434-017-6225-4
  8. Hartig GK. Free flaps in oral cavity reconstruction: when you need them and when you don’t. Int J Radiat Oncol Biol Phys. 2007;69(2 Suppl):19-21.  https://doi.org/10.1016/j.ijrobp.2007.03.068
  9. Molina AR, Citron I, Chinaka F, et al. Calf Perforator Flaps: A Freestyle Solution for Oral Cavity Reconstruction. Plast Reconstr Surg. 2017;139(2): 459-465.  https://doi.org/10.1097/PRS.0000000000002953
  10. Ibrahim B, Rahal A, Bissada E, et al. Reconstruction of medium-size defects of the oral cavity: radial forearm free flap vs facial artery musculo-mucosal flap. J Otolaryngol Head Neck Surg. 2021;50(1):67.  https://doi.org/10.1186/s40463-021-00523-z
  11. Kravtsov SA. Mikrokhirurgicheskaya rekonstruktsiya organov orofaringeal’noj zony zheludochno-sal’nikovym autotransplantatom u onkologicheskikh bol’nykh: Diss. ... kand. med. nauk. M. 2000. (In Russ.).
  12. Wijers OB, Levendag PC, Braaksma MM, et al. Patients with head and neck cancer cured by radiation therapy: A survey of the dry mouth syndrome in long-term survivors. Head Neck. 2002;24(8):737-747.  https://doi.org/10.1002/hed.10129
  13. Matsumoto H, Kimata Y, Ota T, et al. Morphological Changes and Durability of Skin and Mucosal Flaps in Intraoral and Pharyngeal Reconstructions: Long-term Follow-up and Literature Review for Potential Second Carcinomas. Acta Med Okayama. 2021;75(6):725-734.  https://doi.org/10.18926/AMO/62813
  14. Maria L, Ioannis D, Konstantinos V, Fotis I, Konstantinos A. Histological Changes in Nasolabial Cutaneous Flaps Employed in Intraoral Reconstruction. J Maxillofac Oral Surg. 2017;16(3):292-299.  https://doi.org/10.1007/s12663-016-0916-4
  15. Shibahara T, Noma H, Takeda E, Hashimoto S. Morphologic changes in forearm flaps of the oral cavity. J Oral Maxillofac Surg. 2000;58(5):495-499.  https://doi.org/10.1016/s0278-2391(00)90009-0
  16. Wei WI, Lam KH, Lau WF. Fate of skin element of pectoralis major flap in intraoral reconstruction. Arch Otolaryngol Head Neck Surg. 1989;115(3): 360-363.  https://doi.org/10.1001/archotol.1989.01860270102022
  17. Beahm EK, Evans GR, Colome-Grimmer MI. Histologic changes of intraoral free skin flaps. Am J Surg. 1997;174(5):492-494.  https://doi.org/10.1016/s0002-9610(97)00154-2
  18. Badran D, Soutar DS, Robertson AG, et al. Behavior of radial forearm skin flaps transplanted into the oral cavity. Clin Anat. 1998;11(6):379-389.  https://doi.org/10.1002/(SICI)1098-2353(1998)11:6<379::AID-CA3>3.0.CO;2-H
  19. Katou F, Motegi K, Tagami H, et al. Unique inflammatory features noted in intraorally transferred skin flaps: correlation with Candida albicans infection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;87(6):676-684.  https://doi.org/10.1016/s1079-2104(99)70160-5
  20. Behera S, Mohsina S, Tripathy S, et al. Assessment of Clinical and Histological Changes in the Skin Paddle of Pectoralis Major Myocutaneous Flap in Intraoral Reconstruction: A Prospective Cohort Study. Ann Plast Surg. 2020;84(2):173-177.  https://doi.org/10.1097/SAP.0000000000002024
  21. Sinclair A, Johnston E, Badran DH, et al. Histological changes in radial forearm skin flaps in the oral cavity. Clin Anat. 2004;17(3):227-232.  https://doi.org/10.1002/ca.10180
  22. Khan AL, Cloke DJ, Hodgkinson PD, McLean NR, Soames JV. Do intraoral radial forearm free flaps re-mucosalise and is candida infection relevant? Br J Plast Surg. 2001;54(4):299-302.  https://doi.org/10.1054/bjps.2001.3574
  23. Woolgar JA, Triantafyllou A. Histological changes in intra-oral skin flaps. Head Neck Oncol. 2009;1:2.  https://doi.org/10.1186/1758-3284-1-2
  24. Deans JA, Hill J, Welch AR, Soames JV. Late development of a squamous carcinoma in a reconstructed pharynx. J Laryngol Otol. 1990;104(10):827-828. PMID: 2246588. https://doi.org/10.1017/s0022215100114021
  25. Lin Y-S, Mousavi SA, Chen H-C. Free Colon Tissue Transfer for the Management of Xerostomia in Head and Neck Cancer Patients: A Bacteriological Study and Clinical Case Series. J Plast Reconstr Aesthet Surg. 2022;75(8): 2676-2683. https://doi.org/10.1016/j.bjps.2022.04.019
  26. Amendola F, Spadoni D, Losco L, et al. Soft palate reconstruction with free jejunum flap: Impact on the velopharyngeal insufficiency. J Plast Reconstr Aesthet Surg. 2022;75(8):2684-2690. https://doi.org/10.1016/j.bjps.2022.04.044
  27. Bayles SW, Hayden RE. Gastro-omental free flap reconstruction of the head and neck. Arch Facial Plast Surg. 2008;10(4):255-259.  https://doi.org/10.1001/archfaci.10.4.255
  28. Patel RS, Makitie AA, Goldstein DP, et al. Morbidity and functional outcomes following gastro-omental free flap reconstruction of circumferential pharyngeal defects. Head Neck. 2009;31(5):655-663.  https://doi.org/10.1002/hed.21016
  29. Gallagher J, Webb A, Ilankovan V. Gastro-omental free flaps in oral and oropharyngeal reconstruction: surgical anatomy, complications, outcomes. Br J Oral Maxillofac Surg. 2002;40(1):32-36.  https://doi.org/10.1054/bjom.2001.0677
  30. Vidhyadharan S, Thankappan K, Janarthanan R, et al. Gastro-omental free flap for reconstruction of tongue defects. Oral Oncol. 2018;83:134-139.  https://doi.org/10.1016/j.oraloncology.2018.06.023
  31. Wei WI, Lam LK, Yuen PW, et al. Mucosal changes of the free jejunal graft in response to radiotherapy. Am J Surg. 1998;175(1):44-46.  https://doi.org/10.1016/s0002-9610(97)00230-4
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