OBJECTIVE

To study the physiological trophic capabilities of the peritoneum in the experimental and clinical observations.

MATERIAL AND METHODS

Experiments were conducted in 48 adult chinchilla rabbits. Animals underwent resection of small intestine sections of various sizes under anesthesia, the mucous membrane was separated from the resected section, and a fragment of the organ was fixed to the lateral wall of the abdominal cavity or among the intestinal loops. In one group, a section of the intestine was isolated from the peritoneum. The relaparotomy was performed in 1, 3 or 5 days and macro- and microscopically state of the intestinal fragment tissues was assessed. An analysis was carried out in 26 patients with urgent surgical pathology of the abdominal cavity who underwent resection interventions and in the early postoperative period the repeated operations were performed with ability to trace the state of tissues captured in the suture.

RESULTS

It was found that in the groups where an intestine fragment up to 1 cm had contact with the peritoneum the tissues retained their viability at all periods of observation. In the case of fragment 1 cm and more a picture of focal edge necrosis appeared in some observations. In the group with an isolated fragment, the tissue did not retain viability: on day 5, the fragment s was a homogeneous necrotic mass in all observation. Similar results were determined in the clinic in patients with various urgent surgical pathologies of the abdominal organs.

CONCLUSION

Data obtained showing the strong trophic capabilities of the peritoneum. These results are of great practical importance — surgeons should have an understanding of the plastic abilities of the peritoneum and, if possible, apply these data in practice.