The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Mnatsakanyan M.K.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Rubtsova N.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Khamidov D.Kh.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Petrov L.O.

National Medical Research Center for Radiology

Sidorov D.V.

City Clinical Oncology Hospital One Moscow City Healthcare Department

Kaprin A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia;
Peoples’ Friendship University of Russia

Methods for preoperative prediction of postresection hepatic failure

Authors:

Mnatsakanyan M.K., Rubtsova N.A., Khamidov D.Kh., Petrov L.O., Sidorov D.V., Kaprin A.D.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2022;11(5): 70‑77

DOI: 10.17116/onkolog20221105170

Read: 1724 times

Contact the author
Table of contents

METHODS FOR PREOPERATIVE PREDICTION OF POSTRESECTION HEPATIC FAILURE
METHODS FOR PREOPERATIVE PREDICTION OF POSTRESECTION HEPATIC FAILURE

To cite this article:

Mnatsakanyan MK, Rubtsova NA, Khamidov DKh, Petrov LO, Sidorov DV, Kaprin AD. Methods for preoperative prediction of postresection hepatic failure. P.A. Herzen Journal of Oncology. 2022;11(5):70‑77. (In Russ.)
https://doi.org/10.17116/onkolog20221105170

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Abstract:

The paper presents a literature review of the existing classifications and modern methods for the preoperative diagnosis of postresection liver failure. An analysis of literature data demonstrates the relevance of this problem and issues that require further study.

Keywords:

malignant neoplasms of the liver
postresection liver failure
preoperative prognosis

Authors:

Mnatsakanyan M.K.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Rubtsova N.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Khamidov D.Kh.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Petrov L.O.

National Medical Research Center for Radiology

Sidorov D.V.

City Clinical Oncology Hospital One Moscow City Healthcare Department

Kaprin A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia;
Peoples’ Friendship University of Russia

Received:

21.01.2022

Accepted:

07.02.2022

Close metadata

References:

  1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49.  https://doi.org/10.3322/caac.21660
  2. Kaprin AD, Starinskii VV, Shakhzodova AO, eds. The state of oncological care for the population of Russia in 2019. M.: MNIOI im. P.A. Gertsena — filial FGBU «NMINTs radiologii» Minzdrava RF; 2020. (In Russ.).
  3. Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Garrido-Laguna I, et al. NCCN Guidelines Insights: rectal cancer, version 6.2020. J Natl Compr Canc Netw. 2020;18(7):806-815.  https://doi.org/10.6004/jnccn.2020.0032
  4. Agrawal S, Belghiti J. Oncologic resection for malignant tumors of the liver. Ann Surg. 2011;253(4):656-665.  https://doi.org/10.1097/SLA.0b013e3181fc08ca
  5. Murzaliev EM, Mamashev ND, Bebezov BKh. Surgical treatment of colorectal cancer metastases in the liver. Bulletin of the KRSU. 2015;15(4):97-101. (In Russ.).
  6. Kudo M, Gotohda N, Sugimoto M, Kobayashi T, Kojima M, Takahashi S, Konishi M, Hayashi R. Evaluation of liver function using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid enhanced magnetic resonance imaging based on a three-dimensional volumetric analysis system. Hepatol Int. 2018;12(4):368-376.  https://doi.org/10.1007/s12072-018-9874-x
  7. Balzan S, Belghiti J, Farqes O, Ogata S, Sauvanet A, Delefosse D, Durand F. The «50-50 criteria» on postoperative day 5: an accurate predictor of liver failure and death after hepatectomy. Ann Surg. 2005;242(6):824-829.  https://doi.org/10.1097/01.sla.0000189131.90876.9e
  8. Mullen JT, Ribero D, Reddy SK, Donadon M, Zorzi D, Gautam S, Abdalla EK, Curley SA, Capussotti L, Clary BM, et.al. Hepatic insufficiency and mortality in 1,059 noncirrhotic patients undergoing major hepatectomy. J Am Coll Surg. 2007;204(5):854-862.  https://doi.org/10.1016/j.jamcollsurg.2006.12.032
  9. Rahbari NN, Garden OJ, Padbury R, Brooke-Smith M, Crawford M, Adam R, Koch M, Makuuchi M, Dematteo RP, Christophi C, et al. Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS). Surgery. 2011;149(5):713-724.  https://doi.org/10.1016/j.surg.2010.10.001
  10. Rahbari NN, Reissfelder C, Schulze-Bergkamen H, Jäger D, Büchler W, Weitz J, Koch M. Adjuvant therapy after resection of colorectal liver metastases: the predictive value of the MSKCC clinical risk score in the era of modern chemotherapy. BMC Cancer. 2014;14:174.  https://doi.org/10.1186/1471-2407-14-174
  11. Robinson SM, Wilson CH, Burt AD, Manas DM, White SA. Chemotherapy-associated liver injury in patients with colorectal liver metastases: a systematic review and meta-analysis. Ann Surg Oncol. 2012;19(13):4287-4299. https://doi.org/10.1245/s10434-012-2438-8
  12. Tevar AD, Clarke C, Wang J, Rudich SM, Woodle ES, Lentsch AB, Edwards ML. Clinical review of nonalcoholic steatohepatitis in liver surgery and transplantation. J Am Coll Surg. 2010;210(4):515-526.  https://doi.org/10.1016/j.jamcollsurg.2010.01.020
  13. Schneider PD. Preoperative assessment of liver function. Surg Clin North Am. 2004;84(2):355-373.  https://doi.org/10.1016/S0039-6109(03)00224-X
  14. Hyder O, Pulitano C, Firoozmand A, Dodson R, Wolfgang CL, Choti MA, Aldrighetti L, Pawlik TM. A risk model to predict 90-day mortality among patients undergoing hepatic resection. J Am Coll Surg. 2013;216(6):1049-1056. https://doi.org/10.1016/j.jamcollsurg.2013.01.004
  15. Andreatos N, Amini N, Gani F, Margonis GA, Sasaki K, Thompson VM, Bentrem DJ, Hall BL, Pitt HA, Wilson A, Pawlik T.M. Albumin-Bilirubin Score: predicting short-term outcomes including bile leak and post-hepatectomy liver failure following hepatic resection. J Gastrointest Surg. 2017;21(2):238-248.  https://doi.org/10.1007/s11605-016-3246-4
  16. Imamura H, Sano K, Sugawara Y, Kokudo N, Makuuchi M. Assessment of hepatic reserve for indication of hepatic resection: decision tree incorporating indocyanine green test. J Hepatobiliary Pancreat Surg. 2005;12(1):16-22.  https://doi.org/10.1007/s00534-004-0965-9
  17. Ren Z, Xu Y, Zhu S. Indocyanine green retention test avoiding liver failure after hepatectomy for hepatolithiasis. Hepatogastroenterology. 2012;59(115):782-784.  https://doi.org/10.5754/hge11453
  18. Wong JS, Wong GLH, Chan AW, Wong VW, Cheung YS, Chong CN, Wong J, Lee KF, Chan HL, Lai PB. Liver stiffness measurement by transient elastography as a predictor on posthepatectomy outcomes. Ann Surg. 2013;257(5):922-928.  https://doi.org/10.1097/SLA.0b013e318269d2ec
  19. Wissler EH. Identifying a long-standing error in single-bolus determination of the hepatic extraction ratio for indocyanine green. Eur J Appl Physiol. 2011;111(4):641-646.  https://doi.org/10.1007/s00421-010-1678-1
  20. Inal MT, Memiş D, Kargi M, Sut N. Prognostic value of indocyanine green elimination assessed with LiMON in septic patients. J Crit Care. 2009;24(3):329-334.  https://doi.org/10.1016/j.jcrc.2008.11.012
  21. Müller SA, Tarantino I, Corazza M, Pianka F, Fornaro J, Beutner U, Lüthi C, Schmied BM. A rapid and accurate new bedside test to assess maximal liver function: a case report. Patient Saf Surg. 2013;7:11.  https://doi.org/10.1186/1754-9493-7-11.
  22. Sidorov DV, Rubtsova NA, Leont’ev AV, Lozhkin MV, Petrov LO, Lazutina TN, Pylova IV, Korolev PA, Isaeva AG. Methods for assessing the functional status of the liver when planning anatomical resections for primary and metastatic tumors: the current state of the problem, own experience and prospects. Research and practical medicine journal. 2015;2(1):13-20. (In Russ.). https://doi.org/10.17709/2409-2231-2015-2-1-13-20
  23. Shoup M, Gonen M, D’Angelica M, Jarnagin WR, DeMatteo RP, Schwartz LH, Tuorto S, Blumgart LH, Fong Y. Volumetric analysis predicts hepatic dysfunction in patients undergoing major liver resection. J Gastrointest Surg. 2003;7(3):325-330.  https://doi.org/10.1016/s1091-255x(02)00370-0
  24. Abdalla EK, Adam R, Bilchik AJ, Jaeck D, Vauthey JN, Mahvi D. Improving resectability of hepatic colorectal metastases: expert consensus statement. Ann Surg Oncol. 2006;13(10):1271-1280. https://doi.org/10.1245/s10434-006-9045-5
  25. Zorzi D, Laurent A, Pawlik TM, Lauwers GY, Vauthey JN, Abdalla EK. Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases. Br J Surg. 2007;94(3):274-286.  https://doi.org/10.1002/bjs.5719
  26. Krishnamurthy S, Krishnamurthy GT. Technetium- 99m-iminodiacetic acid organic anions: review of biokinetics and clinical application in hepatology. Hepatology. 1989;9(1):139-153.  https://doi.org/10.1002/hep.1840090123
  27. Ghibellini G, Leslie EM, Pollack GM, Brouwer KL. Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies. Pharm Res. 2008;25(8):1851-1860. https://doi.org/10.1007/s11095-008-9597-0
  28. Ekman M, Fjälling M, Friman S, Carlson S, Volkmann R. Liver uptake function measured by IODIDA clearance rate in liver transplant patients and healthy volunteers. Nucl Med Commun. 1996;17(3):235-242.  https://doi.org/10.1097/00006231-199603000-00011
  29. Erdogan D, Heijnen BHM, Bennink RJ, Kok M, Dinant S, Straatsburg IH, Gouma DJ, van Gulik TM. Preoperative assessment of liver function: a comparison of 99mTc-Mebrofenin scintigraphy with indocyanine green clearance test. Liver Int. 2004;24(2):117-123.  https://doi.org/10.1111/j.1478-3231.2004.00901.x
  30. de Graaf W, van Lienden KP, van Gulik TM, Bennink RJ. (99m)Tc-Mebrofenin hepatobiliary scintigraphy with SPECT for the assessment of hepatic function and liver functional volume before partial hepatectomy. J Nucl Med. 2010;51(2):229-236.  https://doi.org/10.2967/jnumed.109.069724
  31. Bennink RJ, Dinant S, Erdogan D, Heijnen BH, Straatsburg IH, van Vliet AK, van Gulik TM. Preoperative assessment of postoperative remnant liver function using hepatobiliary scintigraphy. J Nucl Med. 2004;45(6):965-971. 
  32. Rassam F, Olthof PB, Richardson H, van Gulik TM, Bennink RJ. Practical guidelines for the use of technetium-99m mebrofenin hepatobiliary scintigraphy in the quantitative assessment of liver function. Nucl Med Commun. 2019;40(4):297-307.  https://doi.org/10.1097/MNM.0000000000000973
  33. Krishnamurthy GT, Krishnamurthy S. Nuclear hepatology. A textbook of hepatobiliary diseases. Heidelberg: Springer Berlin; 2000. https://doi.org/10.1007/978-3-662-22654-4
  34. Tsuboyama T, Onishi H, Kim T, Akita H, Hori M, Tatsumi M, Nakamoto A, Nagano H, Matsuura N, Wakasa K, et al. Hepatocellular carcinoma: hepatocyte-selective enhancement at gadoxetic acid-enhanced MR imaging — correlation with expression of sinusoidal and canalicular transporters and bile accumulation. Radiology. 2010;255(3):824-833.  https://doi.org/10.1148/radiol.10091557
  35. Van Beers BE, Pastor CM, Hussain HK. Primovist, eovist: what to expect? J Hepatol. 2012;57(2):421-429.  https://doi.org/10.1016/j.jhep.2012.01.031
  36. Verloh N, Probst U, Utpatel K, Zeman F, Brennfleck F, Werner JM, Fellner C, Stroszczynski C, Evert M, Wiggermann P, et al. Influence of hepatic fibrosis and inflammation: correlation between histopathological changes and Gd-EOB-DTPA-enhanced MR imaging. PLoS One. 2019; 14(5):e0215752. https://doi.org/10.1371/journal.pone.0215752
  37. Costa AF, St-Germain AT, Abdolell M, Smoot RL, Cleary S, Jhaveri KS. Can contrast-enhanced MRI with gadoxetic acid predict liver failure and other complications after major hepatic resection? Clin Radiol. 2017;72(7):598-605.  https://doi.org/10.1016/j.crad.2017.02.004
  38. Asenbaum U, Kaczirek K, Ba-Ssalamah A, Ringl H, Schwarz C, Waneck F, Waneck F, Fitschek F, Loewe C, Nolz R. Post-hepatectomy liver failure after major hepatic surgery: not only size matters. Eur Radiol. 2018;28(11):4748-4756. https://doi.org/10.1007/s00330-018-5487-y
  39. Kim DK, Choi JI, Choi MH, Park MY, Lee YJ, Rha SE, Jung SE. Prediction of posthepatectomy liver failure: MRI with hepatocyte-specific contrast agent versus indocyanine green clearance test. AJR Am J Roentgenol. 2018;211(3):580-587.  https://doi.org/10.2214/AJR.17.19206
  40. Yamada A, Hara T, Li F, Fujinaga Y, Ueda K, Kadoya M, Doi K. Quantitative evaluation of liver function with use of gadoxetate disodium-enhanced MR imaging. Radiology. 2011;260(3):727-733.  https://doi.org/10.1148/radiol.11100586
  41. Geisel D, Lüdemann L, Fröling V, Malinowski M, Stockmann M, Baron A, Gebauer B, Seehofer D, Prasad V, Denecke T. Imaging-based evaluation of liver function: comparison of 99mTc-mebrofenin hepatobiliary scintigraphy and Gd-EOB-DTPA-enhanced MRI. Eur Radiol. 2015;25(5):1384-1391. https://doi.org/10.1007/s00330-014-3536-8
  42. Theilig D, Elkilany A, Schmelzle M, Muller T, Hamm B, Denecke T, Geisel D. Consistency of hepatocellular gadoxetic acid uptake in serial MRI examinations for evaluation of liver function. Abdom Radiol (NY). 2019;44(8):2759-2768. https://doi.org/10.1007/s00261-019-02036-w
  43. Bastati N, Wibmer A, Tamandl D, Einspieler H, Hodge JC, Poetter-Lang S, Rockenschaub S, Berlakovich GA, Trauner M, Herold C, et al. Assessment of orthotopic liver transplant graft survival on gadoxetic acid-enhanced Magnetic Resonance Imaging using qualitative and quantitative parameters. Invest Radiol. 2016;51(11):728-734.  https://doi.org/10.1097/RLI.0000000000000286
  44. Lee NK, Kim S, Kim GH, Heo J, Seo HI, Kim TU, Kang DH. Significance of the «delayed hyperintense portal vein sign» in the hepatobiliary phase MRI obtained with Gd-EOB-DTPA. J Magn Reson Imaging. 2012;36(3):678-685.  https://doi.org/10.1002/jmri.23700
  45. Lee HJ, Hong SB, Lee NG, Kim S, Seo HI, Kim DU, Han SY, Choo KS. Validation of functional liver imaging scores (FLIS) derived from gadoxetic acid-enhanced MRI in patients with chronic liver disease and liver cirrhosis: the relationship between Child-Pugh score and FLIS. Eur Radiol. 2021;31(11):8606-8614. https://doi.org/10.1007/s00330-021-07955-1
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.